503001-27-2Relevant academic research and scientific papers
Palladium-Catalyzed Ring-Forming Alkene Aminoaroylation of Unsaturated Hydrazones and Sulfonamides
Chen, Jun,Yang, Meng-Nan,Chen, Jia-Rong,Xiao, Wen-Jing
, p. 3314 - 3318 (2018/06/11)
The first example of a Pd(OAc)2-catalyzed ring-forming alkene aminoaroylation of unsaturated hydrazones and sulfonamides is described. This protocol features the use of diaryliodonium salts as both oxidants and aryl sources, thus enabling mild
Stereoselective cyclization reactions of IBX-generated alkoxyamidyl radicals
Janza, Birgit,Studer, Armido
, p. 6991 - 6994 (2007/10/03)
In this paper, a method for the generation of alkoxyamidyl radicals is presented. These N-centered radicals can efficiently be formed starting from the corresponding acylated alkoxyamines using IBX as an oxidant. Stereoselective 5-exo and 6-exo reactions with these N-heteroatom-centered radicals leading to isoxazolidines and [1,2]oxazinanes are discussed. The N-O bond in the heterocycles can readily be cleaved with SmI2 to provide N-acylated 1,3-amino alcohols.
Stereoselective electrophilic cyclisation of O-homoallyl hydroxylamine derivatives
Janza, Birgit,Studer, Armido
, p. 2117 - 2123 (2007/10/03)
Electrophilic cyclisations of various O-homoallyl hydroxylamine derivatives are discussed. Non-protected O-homoallyl hydroxylamines undergo oxidative cyclisations to isoxazolines. The new isoxazoline synthesis comprises an initial electrophilic cyclisatio
