50305-81-2

Basic information

• Product Name: CHOLESTEROL TRANS-CINNAMATE
• Synonyms: TRANS-CINNAMIC ACID CHOLESTEROL ESTER;5-CHOLESTEN-3-BETA-OL CINNAMATE;5-CHOLESTEN-3BETA-OL 3-CINNAMATE;CHOLESTEROL TRANS-CINNAMATE;Cholesterolcinnamate;(E)-Cinnamic acid 3β-cholesteryl ester;Cholesterol (E)-cinnamate;Cinnamic acid 3β-cholesteryl ester
• CAS NO: 50305-81-2
• Molecular Formula: C₃₆H₅₂O₂
• Molecular Weight: 516.8
• EINECS: 217-869-9
• Product Categories: Cholesteryl Compounds (Liquid Crystals);Functional Materials;Liquid Crystals & Related Compounds
• Mol File: 50305-81-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: CHOLESTEROL TRANS-CINNAMATE(CAS DataBase Reference)
• NIST Chemistry Reference: CHOLESTEROL TRANS-CINNAMATE(50305-81-2)
• EPA Substance Registry System: CHOLESTEROL TRANS-CINNAMATE(50305-81-2)

Safety Data

• Hazardous Substances Data: 50305-81-2(Hazardous Substances Data)

Usage

General Description

Cholesterol trans-cinnamate is a derivative of cholesterol, a common sterol found in cell membranes and animal tissues. This particular compound is produced by esterification of cholesterol with trans-cinnamic acid, a natural compound found in plants. Cholesterol trans-cinnamate has been studied for its potential use in pharmaceutical and cosmetic applications. It has been found to possess antioxidant, anti-inflammatory, and anti-cancer properties, making it an attractive candidate for development in these fields. Additionally, it has shown potential in enhancing the stability and bioavailability of certain drugs. As a result, research on cholesterol trans-cinnamate continues to explore its potential benefits and applications in various industries.

Upstream product

• 92810-08-7 (cholesteryloxycarbonylmethylen)triphenylphosphoran 
• 100-51-6 benzyl alcohol 
• 26089-39-4 (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl acrylate 
• 57-88-5 cholesterol 
• 102-92-1 Cinnamoyl chloride 
• 140-10-3 (E)-3-phenylacrylic acid 
• 140-10-3 cis-cinnamic acid 
• 59015-50-8 (Z)-3-phenylacryloyl chloride 

Downstream Products

• 140-10-3 (E)-3-phenylacrylic acid 

Relevant articles and documents

Mizoroki-Heck Reaction of Unstrained Aryl Ketones via Ligand-Promoted C-C Bond Olefination

Mizoroki-Heck reaction of unstrained aryl ketone with acrylate/styrene is accomplished via palladium-catalyzed ligand-promoted C-C bond cleavage. Various (hetero)aryl ketones are compatible in the reaction, affording the alkene product in good to excellent yields. Further applications in the late-stage olefination of some drugs, natural products, and fragrance-derived aryl ketones demonstrate the synthetic utility of this protocol. By employing ketone as both the directing group and the leaving group, 1,2-bifunctionalization is achieved via sequential ortho-C-H alkylation/ipso-Heck olefination.

SYNTHESIS AND PROPERTIES OF LIQUID CRYSTALS. III. CHOLESTERYL ESTERS OF SOME CIS,TRANS-ISOMERIC UNSATURATED ACIDS

A series of esters of cholesterol with the cis,trans isomers of unsaturated monocarboxylic acids were synthesized.The effect of the nature and of the configuration of the substituents in relation to the double bond in the acid component of the cholesterol esters on the mesogenic capacity was established.The phase transition temperatures were determined.