59015-50-8

Upstream product

• 140-10-3 cis-cinnamic acid 
• 4610-69-9 (Z)-ethyl cinnamate 
• 100-52-7 benzaldehyde 

Downstream Products

• 21815-91-8 3-chlorobenzo[b]thiophen-2-carbonyl chloride 
• 74502-16-2 2,2,2-trichloroethyl cinnamate 
• 39124-46-4 (Z)-3-phenylacrylamide 
• 1326627-36-4 C₁₈H₁₇NO 
• 1121635-79-7 C₁₉H₂₃NO₂ 
• 863203-37-6 C₁₆H₁₄ClNO₃S 
• 103024-55-1 [1-[(Z)-(3-Phenyl-acryloyl)]-pyrrolidin-(2E)-ylidene]-acetic acid ethyl ester 
• 1990-11-0 cholesteryl cis-cinammate 

Relevant academic research and scientific papers

Pd-Catalyzed α-Selective C-H Functionalization of Olefins: En Route to 4-Imino-β-Lactams

Pd-catalyzed α-olefinic C-H activation of simple α,β-unsaturated olefins has been developed. 4-imino-β-lactam derivatives were readily synthesized via activation of α-olefinic C-H bonds with excellent cis stereoselectivity. A wide range of heterocycles at the β-position are compatible with this reaction. The product of 4-imino-β-lactam derivatives can be readily converted to 2-aminoquinoline which exists extensively in pharmaceutical drugs and natural products.

Key structural features of cis-cinnamic acid as an allelochemical

1-O-cis-cinnamoyl-β-d-glucopyranose is one of the most potent allelochemicals isolated from Spiraea thunbergii Sieb. It is suggested that it derives its strong inhibitory activity from cis-cinnamic acid, which is crucial for phytotoxicity. It was synthesized to confirm its structure and bioactivity, and also a series of cis-cinnamic acid analogues were prepared to elucidate the key features of cis-cinnamic acid for lettuce root growth inhibition. The cis-cyclopropyl analogue showed potent inhibitory activity while the saturated and alkyne analogues proved to be inactive, demonstrating the importance of the cis-double bond. Moreover, the aromatic ring could not be replaced with a saturated ring. However, the 1,3-dienylcyclohexene analogue showed strong activity. These results suggest that the geometry of the C-C double bond between the carboxyl group and the aromatic ring is essential for potent inhibitory activity. In addition, using several light sources, the photostability of the cinnamic acid derivatives and the role of the C-C double bond were also investigated.

Copper(I)-promoted dechlorinative Surzur-Tanner rearrangement of 2,2,2-trichloroethyl carboxylates

(Matrix presented) 2,2,2-Trichloroethyl carboxylates undergo highly efficient dechlorinative Surzur-Tanner rearrangement with 2 equiv of a 1:1 molar mixture of CuCl and bpy in boiling DCE to give 1-chloroethenyl carboxylates in which copper appears to play an important role, probably by coordinating the initial radical or as a Lewis acid catalyst.

SYNTHESIS AND PROPERTIES OF LIQUID CRYSTALS. III. CHOLESTERYL ESTERS OF SOME CIS,TRANS-ISOMERIC UNSATURATED ACIDS

A series of esters of cholesterol with the cis,trans isomers of unsaturated monocarboxylic acids were synthesized.The effect of the nature and of the configuration of the substituents in relation to the double bond in the acid component of the cholesterol esters on the mesogenic capacity was established.The phase transition temperatures were determined.