5032-92-8

Upstream product

• 144776-54-5 2-Pentafluorophenyl-[1,3,2]dioxaphospholane 
• 7196-52-3 Pentafluorphenylphosphonigsaeure 
• 5032-91-7 pentafluorophenyl dichlorophosphine 
• 13648-83-4 bis(diethylamino)-2,3,4,5,6-pentafluorophenylphosphane 
• 344-04-7 bromopentafluorobenzene 
• 879-05-0 2,3,4,5,6-pentafluorophenylmagnesium bromide 

Downstream Products

• 56875-35-5 pentafluorophenylphosphonic acid 

Relevant academic research and scientific papers

Bis(diethylamino)pentafluorophenylphosphane as Valuable Precursor for the Design of Tetrafluorophenylphosphanes, Tetrafluorophenylphosphinic and -phosphonic Acids

Facile replacement of the p-fluorine atom in bis(diethylamino)pentafluorophenylphosphane [(Et2N)2PC6F5] by organolithium derivatives LiR (R = CH3, n-Bu, Ph), lithium alkoxides (R = OMe, OEt) and amides (NMe2, NEt2) is described. The obtained phosphanes p-R-C6F4-P(NEt2)2 are fully characterized. Their acid-catalyzed hydrolysis affords the corresponding phosphinic acids p-R-C6F4-P(O)(H)OH, which are smoothly oxidized by treatment with a mixture of DMSO/I2 to phosphonic acids p-R-C6F4-P(O)(OH)2.

Metaphosphate intermediates from fluoroaromatic precursors

Flow pyrolysis of some 2-aryloxy-1,3,2-dioxaphospholanes with ortho-CF3 or F substituents, either alone or in the presence of methanol, has provided evidence for the formation of methaphosphates as intermediates; these highly reactive species then undergo further reaction, depending on the nature of the substituent.Mass spectrometric studies of the starting materials have also suggested the elimination of ethylene and the formation of methaphosphates to a limited extent.

Synthesis and characterization of some perfluorophenylphosphine derivatives

Bis(pentafluorophenyl)chlorophosphine and pentafluorophenyldichlorophosphine are prepared in good yields from pentafluorophenylmagnesium bromide and phosphorus trichloride. The reactions of the halophosphines with the Lewis bases water, ammonia, dimethylamine, and 2-methylaziridine produced substituted phosphines. Oxidative chlorination of bis(pentafluorophenyl)phosphinamide followed by dehydrohalogenation gave perfluorophenylphosphonitriles. The infrared and pertinent proton magnetic resonance spectra of these compounds are discussed.