503269-74-7Relevant academic research and scientific papers
Difluorphos, an Electron-Poor Disphosphane: A Good Match between Electronic and Steric Features
Jeulin, Severine,De Paule, Sebastien Dupart,Ratovelomanana-Vidal, Virginie,Genet, Jean-Peirre,Champion, Nicolas,Dellis, Philippe
, p. 320 - 325 (2007/10/03)
The π acidity makes the difference: The fluorinated diphosphane, difluorphos, is synthesized (see structure: purple = P, red = O, green = F, gray = C) and its stereoelectronic features are evaluated in theoretical and experimental studies. Its unusual π acidity explains the excellent results obtained with it in ruthenium-mediated asymmetric hydrogenation of fluorinated β-functionalized ketones. These results are better than those obtained with other biphenyl-based diphosphanes.
Novel diphosphines, their complexes with transisition metals and their use in asymmetric synthesis
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Page 7, (2010/02/09)
The invention relates to novel diphosphines, in optically pure or racemic form, of formula (I): in which: R1 and R2 are a (C5-C7)cycloalkyl group, an optionally substituted phenyl group or a 5-membered heteroaryl group; and A is (CH2—CH2) or CF2. The invention further relates to the use of a compound of formula (I) as a ligand for the preparation of a metal complex useful as a chiral catalyst in asymmetric catalysis, and to the chiral metal catalysts comprising at least one ligand of formula (I).
