503272-79-5

Upstream product

• 139557-96-3 (2-iodo-5-methoxyphenyl)methanol 
• 19614-12-1 2-bromo-5-methoxybenzyl bromide 
• 82192-58-3 lithio-1-TIPS-propyne 
• 293732-24-8 2-(bromomethyl)-1-iodo-4-methoxybenzene 
• 100-84-5 1-methoxy-3-methyl-benzene 
• 566912-07-0 4-bromo-3-[4-(triisopropylsilyl)-3-butynyl]phenyl methyl ether 

Downstream Products

• 566912-22-9 3-hexahelicenyl(diphenyl)phosphine oxide 
• 566912-20-7 N-(diphenylmethylene)-3-hexahelicenamine 
• 566912-26-3 2-(6-hepten-3-ynyl)-1-{[2-(6-hepten-3-ynyl)-4-methoxyphenyl]ethynyl}naphthalene 
• 566912-11-6 2-(3-butynyl)-1-{[2-(3-butynyl)-4-methoxyphenyl]ethynyl}naphthalene 
• 566912-10-5 methyl 3-[4-(triisopropylsilyl)-3-butynyl]-4-({2-[4-(triisopropylsilyl)-3-butynyl]-1-naphthyl}ethynyl)phenyl ether 

Relevant academic research and scientific papers

Synthesis of 3-hexahelicenol and its transformation to 3-hexahelicenylamines, diphenylphosphine, methyl carboxylate, and dimethylthiocarbamate

A nonphotochemical synthetic route to 3-hexahelicenol is reported. It involves a key [2+2+2] cycloisomerization of CH3O-substituted triyne that is readily available from 1-methoxy-3-methylbenzene and 1-bromo-2-(bromomethyl)naphthalene. Further

Transition metal control in the reaction of alkyne-substituted phenyl iodides with terminal alkynes: Sonogashira coupling vs cyclic carbopalladation

Reaction between terminal alkynes and phenyl iodides bearing a tethered alkyne unit can be effectively controlled by the nature of a transition metal catalyst. Whereas the use of Pd(0)/Cu(I) promotes the expected Sonogashira coupling to give phenyl alkyne