503560-10-9

Downstream Products

• 482315-18-4 N-[(1S)-2-hydroxy-1-(tert-butyldimethylsilanyloxymethyl)-3-butenyl]-benzamide 
• 208935-32-4 (4S,trans)-4,5-dihydro-4-(tert-butyldimethylsilanyloxymethyl)-2-phenyloxazoline 
• 497227-96-0 ((4S,5S)-2-Phenyl-5-vinyl-4,5-dihydro-oxazol-4-yl)-methanol 
• 482315-14-0 (4R,5S)-2-Phenyl-5-vinyl-4,5-dihydro-oxazole-4-carboxylic acid methyl ester 
• 497227-95-9 N-((1S)-2-acetoxy-1-(tert-butyldimethylsilanyloxymethyl)-3-butenyl)-benzamide 
• 503560-09-6 3-((4S,trans)-4,5-dihydro-4-methyl-2-phenyloxazol-5-yl)-N-methoxy-N-methyl propionamide 
• 497227-89-1 (4S,5S)-4-Hydroxymethyl-2-phenyl-5-vinyl-4,5-dihydro-oxazole-4-carboxylic acid methyl ester 
• 1027989-75-8 (4S,5R)-5-Formyl-4-methoxymethoxymethyl-2-phenyl-4,5-dihydro-oxazole-4-carboxylic acid methyl ester 
• 503560-12-1 3-(4-hydroxymethyl-2-phenyl-4,5-dihydro-oxazol-5-yl)-N-methoxy-N-methyl-propionamide 
• 497227-90-4 (4S,5S)-4-Methoxymethoxymethyl-2-phenyl-5-vinyl-4,5-dihydro-oxazole-4-carboxylic acid methyl ester 
• 503560-13-2 3-(4-iodomethyl-2-phenyl-4,5-dihydro-oxazol-5-yl)-N-methoxy-N-methyl-propionamide 
• 503560-07-4 (2E)-3-((4S,trans)-4,5-dihydro-4-(tert-butyldimethylsilanyloxymethyl)-2-phenyloxazol-5-yl)-acrylic acid methyl ester 
• 497227-92-6 (3aS,6R,6aR)-6-((E)-3-Iodo-allyl)-3a-methoxymethoxymethyl-2-phenyl-6,6a-dihydro-3aH-furo[3,4-d]oxazol-4-one 
• 503560-08-5 3-((4S,trans)-4,5-dihydro-4-(tert-butyldimethylsilanyloxymethyl)-2-phenyloxazol-5-yl)-propionic acid methyl ester 

Relevant academic research and scientific papers

Total synthesis of sphingofungin F.

[reaction: see text] A concise, stereocontrolled synthesis of sphingofungin F was achieved. Key features involve diastereoselective oxazoline formation catalyzed by palladium(0), MgBr(2)-promoted gamma-alkoxy allylic stannane addition, and palladium(0)-ca

Stereoselective intramolecular cyclization of isopentenyl benzamide via π-allylpalladium complex catalyzed by Pd(0)

An efficient procedure was developed to synthesize oxazoline as key intermediate in the total synthesis of (+)-lactacystin using palladium(0)-catalyzed intramolecular cyclization of isopentenyl benzamide via a π-allylpalladium complex. A convenient and ef

Stereoselective synthesis of (+)-spectaline

Our synthesis of (+)-spectaline revealed that the methodology involving diastereoselective palladium(0)-catalyzed oxazoline formation and intramolecular reductive amination by catalytic hydrogenation of an oxazoline is an effective method for the asymmetric synthesis of natural products possessing complex functionalized piperidine cores.

Total synthesis of myriocin

A concise, stereocontrolled synthesis of myriocin was achieved. Key features involve diastereoselective oxazoline formation catalyzed by palladium(0), MgBr2-promoted allylic stannane addition, and palladium(0)-catalyzed coupling of a vinyl iodide with an organozinc reagent.