50358-40-2 Usage
Uses
Used in Pharmaceutical Industry:
8-methylquinolin-5-amine is used as a pharmaceutical intermediate for the synthesis of various drugs due to its versatile chemical structure and potential to be modified for specific therapeutic effects.
Used in Medicinal Chemistry:
8-methylquinolin-5-amine is utilized as a building block in the development of new compounds with antimalarial and antitumor properties, leveraging its inherent biological activities for the treatment of diseases.
Used in Chemical Synthesis:
8-methylquinolin-5-amine serves as a key component in the synthesis of complex organic molecules, taking advantage of its reactive amino and methyl groups for further functionalization and the creation of novel chemical entities.
Used in Research and Development:
8-methylquinolin-5-amine is employed as a subject of study in research aimed at understanding its pharmacological properties, optimizing its synthesis, and exploring its potential applications in various therapeutic areas.
Check Digit Verification of cas no
The CAS Registry Mumber 50358-40-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,3,5 and 8 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 50358-40:
(7*5)+(6*0)+(5*3)+(4*5)+(3*8)+(2*4)+(1*0)=102
102 % 10 = 2
So 50358-40-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H10N2/c1-7-4-5-9(11)8-3-2-6-12-10(7)8/h2-6H,11H2,1H3
50358-40-2Relevant academic research and scientific papers
TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS
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, (2013/11/05)
The present disclosure is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, as m PGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (m PGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthma, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases.
8-Methylquinoline palladacycles: Stable and efficient catalysts for carbon-carbon bond formation
Evans, Paul,Hogg, Paul,Grigg, Ronald,Nurnabi, Mohamed,Hinsley, Joanne,Sridharan, Visuvanathar,Suganthan, Selvaratnam,Korn, Stewart,Collard, Simon,Muir, Jane E.
, p. 9696 - 9704 (2007/10/03)
Cyclopalladated, phosphine free, 8-methyl quinoline based complexes (2a-j) are excellent catalysts for the Heck vinylation of aryl iodides and bromides with turnover numbers of greater than 25 million observed in some cases. The catalysts are air and moisture stable.
