50397-65-4 Usage
Uses
Used in Pharmaceutical Research:
(4-Bromophenylsulfonyl)acetic acid methyl ester is used as a research compound for its potential anti-proliferative properties. It is valuable in the development of new drugs and therapies, particularly those aimed at inhibiting the proliferation of cancer cells.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (4-Bromophenylsulfonyl)acetic acid methyl ester serves as a key intermediate or building block for the synthesis of more complex molecules with therapeutic potential. Its unique structure and properties make it a useful tool in the design and optimization of novel pharmaceutical agents.
Used in Drug Development:
(4-Bromophenylsulfonyl)acetic acid methyl ester is utilized as a starting material or a component in the development of new drugs. Its potential anti-proliferative activity makes it a promising candidate for the creation of medications targeting various diseases, including cancer.
Used in Laboratory Settings:
(4-Bromophenylsulfonyl)acetic acid methyl ester is employed as a reagent in laboratory experiments and studies. It is used to investigate the compound's properties, interactions, and potential applications in various fields, such as drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 50397-65-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,3,9 and 7 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 50397-65:
(7*5)+(6*0)+(5*3)+(4*9)+(3*7)+(2*6)+(1*5)=124
124 % 10 = 4
So 50397-65-4 is a valid CAS Registry Number.
50397-65-4Relevant academic research and scientific papers
Synthesis of Sulfones via Ru(II)-Catalyzed Sulfination of Boronic Acids
Gulbe, Krista,Turks, Mā ris
, p. 5660 - 5669 (2020/05/19)
Ruthenium(II) complexes catalyze the insertion of sulfur dioxide into (het)aryl and alkenyl boronic acids. The transmetalation-sulfination process proceeds with DABSO in the presence of 5 mol % RuCl2(PPh3)3 in methanol at 100 °C. The intermediate sulfinate salt can be quenched with various electrophiles such as alkyl halides, epoxides, Michael acceptors, and λ3-iodanes in moderate to good yields. The reported sulfone synthesis can be performed either as a direct one-pot or one-pot two-step procedure depending on the reactivity of the electrophile.
Applicability of Hammett Equation to Kinetics of Acid-catalysed Esterification of meta- and para-Substituted Phenylmercaptoacetic and Phenylsulphonylacetic Acids with Methanol
Baliah, V.,Gurumurthy, R.
, p. 725 - 726 (2007/10/02)
Rate constants have been determined for the acid-catalysed esterification of meta- and para-substituted phenylmercaptoacetic and phenylsulphonylacetic acids with methanol using hydrogen chloride as catalyst.The lower reactivities of phenylmercaptoacetic acids compared to those of the corresponding phenoxyacetic acids are discussed.
