50434-43-0Relevant academic research and scientific papers
Palladium-catalyzed decarboxylative coupling of potassium nitrophenyl acetates with aryl halides
Shang, Rui,Huang, Zheng,Chu, Ling,Fu, Yao,Liu, Lei
supporting information; experimental part, p. 4240 - 4243 (2011/10/09)
A palladium-catalyzed decarboxylative cross-coupling of potassium 2- and 4-nitrophenyl acetates with aryl chlorides and bromides has been developed. Because the nitro group can be readily converted to many other functional groups, the new reaction provides a useful method for the preparation of diverse 1,1-diaryl methanes and their derivatives.
Direct amino acid-catalyzed cascade reductive alkylation of arylacetonitriles: High-yielding synthesis of ibuprofen analogs
Ramachary, Dhevalapally B.,Shiva Prasad
scheme or table, p. 5246 - 5251 (2010/11/03)
A novel approach for a one-pot, three-component reductive alkylation (TCRA) reaction of arylacetonitriles-containing electron-withdrawing groups with aldehydes/ketones and 1,4-dihydropyridine via iminium-catalysis has been developed. Many TCRA reaction products have direct applications in agricultural and pharmaceutical chemistry.
FUSED PYRIMIDINE COMPOUNDS AND THEIR USE AS PHARMACEUTICALS
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, (2008/06/13)
Pharmaceutical compounds which are azolo-fused pyrimidine compounds having the formula STR1 in which =A--B--together with the pyrimidine ring forms a) a pyrazolo[1,5-a]pyrimidine of formula (A), STR2 b) a [1,2,4]triazolo[1,5-a]pyrimidine of formula (B), STR3 c) an imidazo[1,5-a]pyrimidine of formula (C), STR4 or d) an imidazo[1, 2-a]pyrimidine of formula (D), STR5
Anti-coagulants of the 4-hydroxycoumarin type and rodenticidal compositions (baits) comprising such anti-coagulants
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, (2008/06/13)
Compounds having blood-anticoagulant properties of the general molecular formula: STR1 in which Z represents a halogen atom, preferably a chlorine atom, and n is 0, 1 or 2 and R4 represents either (1) a grouping which comprises a phenylene radical attached directly or indirectly to the tetralin ring and having in the para position (with respect to such attachment) an electron-withdrawing atom or group whose rotational volume substantially does not exceed that of a phenyl group and which forms together with said phenylene radical a polarizable structure, or (2) a grouping selected from: STR2 or (3) a grouping which comprises a phenylene radical attached directly to the tetralin ring and having in the para position (with respect to such attachment) a substituted furanyl or thiophenyl radical attached thereto directly or through oxygen and/or methylene, said furanyl or thiophenyl radical having such an electron-withdrawing atom or group as a substituent in a position forming with the furanyl or thiophenyl radical a polarizable structure, compounds of the type (1) in which R4 contains two phenylene radicals linked essentially linearly by an aliphatic chain comprising a methylene radical or radicals and optionally at least one oxygen or sulphur atom being preferred. Also included are the processes for the preparation of such compound; rodenticidal compositions containing them; and a method for controlling rodents by applying such a composition.
Response of Acidity and Magnetic Rtesonance Properties to Aryl Substitution in Carbon Acids and Derived Carbanions: 2- and 3-Arylindenes
Greifenstein, Linda G.,Lambert, Joseph B.,Nienhuis, Ronald J.,Fried, Herbert E.,Pagani, Giorgio A.
, p. 5125 - 5132 (2007/10/02)
Substitution in the aryl ring of 2- and 3-arylindenes has been used to examine the acidity of these hydrocarbons and the charge density and ion pair structure of their anions.Acidities were measured for the 2-arylindenes both in pure Me2SO and in Me2SO-H2
