50438-39-6Relevant academic research and scientific papers
Copper-mediated trifluoroethoxylation of vinyl bromides
Ding, Jianping,You, Yi,Weng, Zhiqiang
, p. 1724 - 1727 (2016)
Vinyl bromides were subjected to the trifluoroethoxylation reactions with copper reagent [(phen)2Cu][OCH2CF3] at 80°C in DMF with the presence of NaOt-Bu to afford the trifluoroethyl vinyl ethers in good yields. A range of functional groups, such as cyano, nitro, alkoxy, trifluoromethyl, halide, and heterocyclic groups were well tolerated. This approach is also amenable to being performed out on gram scales.
Facile access to fluorinated aryl and vinyl ethers through copper-catalysed reaction of fluoro alcohols
Vukga, Daniela,Legros, Juelien,Crousse, Benoit,Bonnet-Delpon, Daniele
experimental part, p. 3513 - 3518 (2009/12/01)
Fluorinated alcohols react with aryl and vinyl halides by copper-catalysed cross-coupling reactions to afford the corresponding ethers. With trifluoroethanol (TFE) the reaction proceeds with both iodides and bromides and a wide range of aromatic substituents are tolerated. When higher fluorinated homologues such as C7P15CH2OH were used, the corresponding products were obtained in good yields, thus of-fering an interesting entry to fluorous tagging.
