504414-60-2

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 916426-85-2 (+/-)-(3-(methoxymethoxy)hex-5-enyl)benzene 
• 60340-28-5 1-phenylhex-5-en-3-ol 
• 504414-61-3 3-hydroxy-5-phenylpentanethioic acid S-benzyl ester 
• 504414-72-6 3-methoxymethoxy-5-phenyl-pentanethioic acid S-benzyl ester 

Relevant academic research and scientific papers

Prins cyclization of α-bromoethers under basic conditions

α-Bromoethers have been found to undergo Prins-type cyclization under basic conditions and without the need to add a promoter. The products are those derived from a Markovnikov addition on the pendant alkene. However, the stereochemistry and even the structure of the products sometimes differ from those expected with the classical Lewis-acid-catalyzed Prins reaction of acetals.

An exceptionally mild catalytic thioester aldol reaction inspired by polyketide biosynthesis

This report details our discovery of a new catalytic ester aldol reaction using malonic acid half thioesters (MAHTs) that directly affords β-hydroxythioesters. The reaction is catalyzed by combination of a Cu(II) salt and an amine base, and it can be perf