504414-72-6Relevant academic research and scientific papers
An exceptionally mild catalytic thioester aldol reaction inspired by polyketide biosynthesis
Lalic, Gojko,Aloise, Allen D.,Shair, Matthew D.
, p. 2852 - 2853 (2007/10/03)
This report details our discovery of a new catalytic ester aldol reaction using malonic acid half thioesters (MAHTs) that directly affords β-hydroxythioesters. The reaction is catalyzed by combination of a Cu(II) salt and an amine base, and it can be perf
