5045-65-8

Basic information

• Product Name: 3-(4-chlorophenyl)-glutaric acid monomethyl ester
• Synonyms: 3-(4-chlorophenyl)-glutaric acid monomethyl ester
• CAS NO: 5045-65-8
• Molecular Weight: 256.686
• Mol File: 5045-65-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(4-chlorophenyl)-glutaric acid monomethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-chlorophenyl)-glutaric acid monomethyl ester(5045-65-8)
• EPA Substance Registry System: 3-(4-chlorophenyl)-glutaric acid monomethyl ester(5045-65-8)

Safety Data

• Hazardous Substances Data: 5045-65-8(Hazardous Substances Data)

Upstream product

• 35271-74-0 3-(4-chlorophenyl)pentane-1,5-dioic acid 
• 104-88-1 4-chlorobenzaldehyde 
• 67-56-1 methanol 
• 53911-68-5 3-(4-chlorophenyl)glutaric anhydride 

Relevant articles and documents

Enzymatic desymmetrization of 3-arylglutaric acid anhydrides

Optically active (R)- and (S)-3-arylglutaric acid monoesters 3 were synthesized in quantitative yields and good stereoselectivities by lipase-catalyzed desymmetrization of the corresponding 3-arylglutaric anhydrides 2 with alcohols. It was observed that the stereochemical outcome of the reaction was influenced by the substituents present on the aromatic ring. The influence of the enzyme, alcohol, and solvent was systematically examined. Absolute configurations of the monoesters 3 were assigned by chemical correlation to corresponding lactones 4.