50468-24-1

Basic information

• Product Name: ethyl 3-phenyl-1-tosylaziridine-2-carboxylate
• Synonyms: ethyl 3-phenyl-1-tosylaziridine-2-carboxylate
• CAS NO: 50468-24-1
• Molecular Weight: 345.419
• Mol File: 50468-24-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: ethyl 3-phenyl-1-tosylaziridine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-phenyl-1-tosylaziridine-2-carboxylate(50468-24-1)
• EPA Substance Registry System: ethyl 3-phenyl-1-tosylaziridine-2-carboxylate(50468-24-1)

Safety Data

• Hazardous Substances Data: 50468-24-1(Hazardous Substances Data)

Upstream product

• 121-39-1 ethyl 3-phenylglycidate 
• 98-59-9 p-toluenesulfonyl chloride 
• 103-36-6 ethyl 3-phenyl-2-propenoate 
• 55962-05-5 [N-(p-tolylsulfonyl)imino]phenyliodinane 
• 4192-77-2 ethyl cinnamate 
• 127-65-1 chloroamine-T 

Downstream Products

• 97478-38-1 5-ethenyl-2-phenyl-1-tosyl-3-pyrroline 
• 101719-48-6 ethyl 3-(4-methylphenylsulfonamido)-3-phenylpropanoate 
• 97478-49-4 3-Phenyl-1-(toluene-4-sulfonyl)-aziridine-2-carbaldehyde 

Relevant articles and documents

Aziridination of Olefins

A process for aziridination of olefins using NaIO4/alkali metal bromide/H+/Chloramine-T combination in presence of dipolar aprotic solvent under ambient conditions to obtain aziridines is disclosed.

Efficient ring opening reactions of N-tosyl aziridines with amines and water in presence of catalytic amount of cerium(IV) ammonium nitrate

While methyl- and benzylamines opened N-tosyl aziridines 1 very efficiently in acetonitrile with complete regio- and stereoselectivity to give the corresponding diamines 2 and 3, respectively, in excellent yields, similar openings with water could only be achieved in the presence of a catalytic amount of cerium(IV) ammonium nitrate under very mild conditions furnishing the amino alcohols 4.

Copper-Catalyzed Aziridination of Olefins by (N-(p-Toluenesulfonyl)imino)phenyliodinane

The Cu(I)- or Cu(II)-catalyzed aziridination of both electron-rich and electron-deficient olefins employing (N-(p-toluenesulfonyl)imino)phenyliodinane, PhI=NTs, as the nitrene precursor, affords N-tosylaziridines in yields ranging between 55percent - 95pe