50515-43-0

Basic information

• Product Name: 3-methoxy-1-phenyl-but-2t-en-1-one
• Synonyms: 3-methoxy-1-phenyl-but-2t-en-1-one
• CAS NO: 50515-43-0
• Molecular Weight: 176.215
• Mol File: 50515-43-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-methoxy-1-phenyl-but-2t-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methoxy-1-phenyl-but-2t-en-1-one(50515-43-0)
• EPA Substance Registry System: 3-methoxy-1-phenyl-but-2t-en-1-one(50515-43-0)

Safety Data

• Hazardous Substances Data: 50515-43-0(Hazardous Substances Data)

Upstream product

• 77-78-1 dimethyl sulfate 
• 186581-53-3 diazomethane 
• 93-91-4 1-phenylbutan-1,3-dione 

Downstream Products

• 32933-05-4 3-acetyl-4-methyl-2-phenylfuran 
• 32933-06-5 (2,4-Dimethyl-furan-3-yl)-phenyl-methanone 
• 122552-45-8 2-Bromo-3-methoxy-1-phenyl-3-prop-2-ynyloxy-butan-1-one 
• 50487-01-9 (2E)-3-methoxy-1-phenylbut-2-en-1-one 

Relevant articles and documents

The Allopolarization Principle and its Applications, VI. The Alkylation of Enolate Anions: Polarity and Regioselectivity

The O/C methylation ratio in the reaction of sodium enolates with dimethylsulfate depends on the polar (electronic) effect of substituents.The relative ?-charge density Px/y = lx/ly can be used as a measure for the polarity of ambifunctional anions; in case of enolate anions PO/C = lO/lC.The change of the regioselectivity Sf = log QO/QC in the alkylation of enolates is a function of a change in the polarity PO/C; ΔSf=f(ΔPx/y).The polar effect of substituents influences the charge control during the alkylation process via a change of the polarity of the enolate system: The higher the polarity of the anion, the stronger the charge control and the higher the yield of enol ether (O-alkylation). - Keywords: Alkylation, Enolate Anions