50487-01-9

Upstream product

• 917-64-6 methyl magnesium iodide 
• 85127-45-3 methyl 3-(2H-imidazol-1-yl)-3-phenylacrylate 
• 147726-34-9 (Z)-3-Methoxy-3-methylsulfanyl-1-phenyl-propenone 
• 67-56-1 methanol 
• 93-91-4 1-phenylbutan-1,3-dione 
• 50515-43-0 3-methoxy-1-phenyl-but-2t-en-1-one 

Relevant academic research and scientific papers

Ytterbium triflate catalyzed synthesis of β-keto enol ethers

β-Keto enol ethers have been synthesized in very good yield in solvent-free conditions from differently substituted alcohols and β-diketones in the presence of Yb(OTf)3 as catalyst. The method is applicable to both cyclic and acyclic β-diketones with only slight differences in the experimental procedure.

Highly efficient and selective displacement of alkylthio group on acylketene O,S-acetals by organocopper reagents: A novel route to 2-alkoxy/aryloxy-1-alkenylketones

Acylketene O,S-acetals 1a-k undergo efficient and selective conjugate displacement of alkylthio group with organocopper(I) reagents to afford the corresponding 6-alkoxy/aryloxy enones 2-21 in good yields.

THE REGIOSELECTIVE PREPARATION OF 1-ALKEN-3-ONES BY THE REACTION OF 3-(1-IMIDAZOLYL)-2-ALKEN-1-ONES WITH ORGANOMETALLIC COMPOUNDS

3-(1-Imidazolyl)-2-alken-1-ones, having substituent on the C-3 carbon, reacted with organometallic compounds to afford 3-(1-imidazolyl)-2-alken-1-ols.By the treatment of the products with sulfuric acid, 1-alken-3-ones, which were the positional isomers of the Michael addition products, was obtained regioselectively in good yields under mild conditions.Sodium borohydride reduction was also investigated.