50515-48-5

Upstream product

• 2578-33-8 D-glutamic acid-5-benzyl ester 
• 3392-05-0 Boc-Ala-O-N-hydroxysuccinimide 
• 34404-30-3 N-(tert-butoxycarbonyl)-D-glutamic acid 1-benzyl ester 
• 100-39-0 benzyl bromide 
• 80162-36-3 Boc-L-alanyl-D-glutamic acid 

Downstream Products

• 678159-24-5 N-tert-butoxycarbonyl-L-alanyl-D-glutamic acid α-benzyl-γ-p-nitrophenyl ester 
• 50515-47-4 N-tert-butoxycarbonyl-L-alanyl-D-glutaminyl-(α-benzyl)-γ-N-ε-benzyloxycarbonyl-L-lysinyl-D-alanyl-D-alanine benzyl ester 
• 76490-19-2 (R)-2-[(S)-2-(2-Acetoxy-propionylamino)-propionylamino]-4-[(1S,5R)-5-tert-butoxycarbonylamino-6-(N'-tert-butoxycarbonyl-hydrazino)-1-(carboxymethyl-carbamoyl)-6-oxo-hexylcarbamoyl]-butyric acid benzyl ester 
• 76490-22-7 (2R,6S)-2-Amino-6-{(R)-4-carboxy-4-[(S)-2-(2-hydroxy-propionylamino)-propionylamino]-butyrylamino}-6-(carboxymethyl-carbamoyl)-hexanoic acid 
• 1428244-77-2 C₄₄H₅₅N₇O₁₁ 
• 96922-04-2 (2S,6S)-2-Benzyloxycarbonylamino-6-[(S)-4-benzyloxycarbonyl-4-((R)-2-tert-butoxycarbonylamino-propionylamino)-butyrylamino]-6-(benzyloxycarbonylmethyl-carbamoyl)-hexanoic acid ethyl ester 
• 78057-80-4 N²-1-benzyl-N-(N-lauroyl-L-alanyl)-γ-D-glutamyl>-N⁶-benzyloxycarbonyl-L-2,6-diaminopimelamic acid 
• 78057-77-9 RP 56142 
• 78057-59-7 O¹-benzyl-N-(N-lauroyl-L-alanyl)-D-glutamic acid 
• 76490-22-7 L-lactoyl-L-Ala-γ-D-Glu(α-OH)-(L)meso-A₂pm(L)-Gly 
• 76490-07-8 L-lactoyl(OAc)-L-Ala-D-Glu(OH)OBzl 
• 76490-19-2 L-lactoyl(OAc)-L-Ala-γ-D-Glu(α-OBzl)-(L)-Boc-(D)meso-A₂pm(D)-NHNHBoc-(L)-Gly 
• 78057-61-1 L-alanyl-O¹-benzyl-D-glutamic acid hydrochloride 
• 78665-22-2 (R)-2-((S)-2-Amino-propionylamino)-pentanedioic acid 1-benzyl ester 

Relevant academic research and scientific papers

Synthesis of Bacterial-Derived Peptidoglycan Cross-Linked Fragments

Peptidoglycan (PG) is the core structural motif of the bacterial cell wall. Fragments released from the PG serve as fundamental recognition elements for the immune system. The structure of the PG, however, encompasses a variety of chemical modifications among different bacterial species. Here, the applicability of organic synthetic methods to address this chemical diversity is explored, and the synthesis of cross-linked PG fragments, carrying biologically relevant amino acid modifications and peptide cross-linkages, is presented using solution and solid phase approaches.

N-Methylimidazolium chloride-catalyzed pyrophosphate formation: Application to the synthesis of Lipid i and NDP-sugar donors

N-Methylimidazolium chloride is found to catalyze a coupling reaction between monophosphates and activated phosphorous-nitrogen intermediates such as a phosphorimidazolide and phosphoromorpholidate to form biologically important unsymmetrical pyrophosphat