50536-58-8

Basic information

• Product Name: 5-bromo-4-methyl-1H-indole-2-carboxylic acid
• Synonyms: 5-bromo-4-methyl-1H-indole-2-carboxylic acid;5-Bromo-4-methylindole-2-carboxylic acid
• CAS NO: 50536-58-8
• Molecular Formula: C₁₀H₈BrNO₂
• Molecular Weight: 254.08002
• Mol File: 50536-58-8.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-bromo-4-methyl-1H-indole-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-4-methyl-1H-indole-2-carboxylic acid(50536-58-8)
• EPA Substance Registry System: 5-bromo-4-methyl-1H-indole-2-carboxylic acid(50536-58-8)

Safety Data

• Hazardous Substances Data: 50536-58-8(Hazardous Substances Data)

Upstream product

• 81803-45-4 ethyl 2-azido-3-(2-methylphenyl)propenoate 
• 529-20-4 2-methylphenyl aldehyde 
• 16732-80-2 4-methyl-1H-indole-2-carboxylic acid ethyl ester 
• 1857296-39-9 methyl 5-bromo-4-methyl-1H-indole-2-carboxylate 
• 83647-40-9 3-bromo-2-methylbenzaldehyde 
• 83647-43-2 3-bromo-2-methylbenzyl alcohol 
• 76006-33-2 3-bromo-2-methylbenzoic acid 
• 671215-69-3 ethyl 5-bromo-4-methyl-1H-indole-2-carboxylate 

Downstream Products

• 671215-70-6 4-Methyl-1H-indole-5-carbonitrile 

Relevant articles and documents

Regioselective Functionalization of 4-Methyl-1H-indole for Scalable Synthesis of 2-Cyano-5-formyl-4-methyl-1H-indole

We report a five-step synthesis of 2-cyano-5-formyl-4-methyl-1H-indole through sequential functionalization of readily available 4-methyl-1H-indole. Cyano and aldehyde functionalities are regioselectively installed at the 2 and 5 position, respectively. T

THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF

The present disclosure provides compounds and methods for inhibiting the interaction of menin with its upstream or downstream signaling molecules including but not limited to MLL1, MLL2 and MLL-fusion oncoproteins. Compounds of the disclosure may be used

Indolyl derivatives

Compounds of formula I are provided as well as pharmaceutically acceptable salts and esters thereof, wherein R1 to R8, A, A1 and n have the significance indicated in the specification.