50552-12-0

Upstream product

• 16695-87-7 1,4-dimethylcyclohex-3-ene-1-carboxylic acid 
• 139278-33-4 (1R,4S)-3-Methacryloyl-1,7,7-trimethyl-3-azabicyclo<2.2.1>heptan-2-one 
• 24326-88-3 (1S)-4,7,7-trimethyl-2-azabicyclo<2.2.1>heptan-3-one 
• 139404-50-5 (1S,4R)-2-((R)-1,4-Dimethyl-cyclohex-3-enecarbonyl)-4,7,7-trimethyl-2-aza-bicyclo[2.2.1]heptan-3-one 
• 78-79-5 isoprene 
• 84895-35-2 (Z)-3-chloro-2-methylpropenal 
• 78-85-3 2-methylpropenal 
• 58911-05-0 1,4-Dimethyl-3-cyclohexen-1-carbonsaeure-methylester 

Downstream Products

• 130604-82-9 1,4-Dimethyl-6-exo-phenylseleno-2-oxabicyclo<2.2.2>octane 
• 95760-48-8 1,4-Dimethyl-3-cyclohexen-1-acetonitril 
• 95760-49-9 1,4-Dimethyl-3-cyclohexen-1-essigsaeure 
• 933-44-8 1,4-dimethyl-cyclohex-3-enecarbaldehyde 
• 95760-47-7 <(1,4-Dimethyl-3-cyclohexenyl)methyl>-p-toluolsulfonat 
• 50552-16-4 1,4-Dimethyl-4-nitrosooxymethyl-cyclohexene 

Relevant academic research and scientific papers

First Synthesis of rac-Homofenchone (1,4,4-Trimethylbicyclooctan-3-one)

The rac-homofenchone (2), which was previously unknown, is prepared starting from the cyclohexenecarboxylate 4 via the bicyclooctene 13 by two independent routes.The key steps are either the intramolecular acylation of a C=C bond in 9 induced by trifluoroacetic acid anhydride, or the BF3-catalyzed decomposition of the diazomethyl ketone 15.From 13 a direct path leads to homofenchone (2), the NMR spectra of which were fully assigned.

Total Synthesis of Halogenated Monoterpene Marine Natural Products via the Diels-Alder Reaction

This work represents the first de novo synthetic approach to the halogenated, monocyclic monoterpenes isolated from red algae belonging to the genus Plocamium.The total syntheses of two natural products, i.e., epi-plocamene D (2) and the allylic chloride