95760-49-9

Upstream product

• 95760-48-8 1,4-Dimethyl-3-cyclohexen-1-acetonitril 
• 78-79-5 isoprene 
• 95760-47-7 <(1,4-Dimethyl-3-cyclohexenyl)methyl>-p-toluolsulfonat 
• 58911-05-0 1,4-Dimethyl-3-cyclohexen-1-carbonsaeure-methylester 
• 50552-12-0 1,4-Dimethyl-3-cyclohexen-1-methanol 

Relevant academic research and scientific papers

First Synthesis of rac-Homofenchone (1,4,4-Trimethylbicyclooctan-3-one)

The rac-homofenchone (2), which was previously unknown, is prepared starting from the cyclohexenecarboxylate 4 via the bicyclooctene 13 by two independent routes.The key steps are either the intramolecular acylation of a C=C bond in 9 induced by trifluoroacetic acid anhydride, or the BF3-catalyzed decomposition of the diazomethyl ketone 15.From 13 a direct path leads to homofenchone (2), the NMR spectra of which were fully assigned.