50617-98-6Relevant academic research and scientific papers
Copper-mediated oxidative homocoupling and rearrangement of N-alkoxyamides: An efficient method for the preparation of aromatic esters
Duan, Xiyan,Yang, Kun,Tian, Shuang,Ma, Junying,Li, Yaning,Zou, Jiao,Zhang, Dongliang,Cui, Huanqing
, p. 4634 - 4637 (2015)
N-Alkoxyamides are successfully converted into their corresponding esters in a moderate to satisfactory yields via copper-catalyzed oxidative homocoupling and Heron rearrangement. The process tolerates a wide variety of functional groups and allows the synthesis of sterically hindered ester products not readily accessible by traditional acylation chemistry. A radical-mediated pathway has been tentatively proposed for the oxidative process.
A new synthesis of nitriles from N-alkoxyimidoyl halides with zinc
Sakamoto,Mori,Takizawa,Kikugawa
, p. 750 - 752 (2007/10/02)
Both aliphatic and aromatic nitriles are obtained from the corresponding N-methoxy-, N-benzyloxy- or N-tert-butoxyimidoyl halides with zinc in a acetic acid/dimethylformamide mixture (1:1).
