5065-11-2

Upstream product

• 5651-55-8 3-(benzyloxy)-4,5-dimethoxybenzoic acid 

Downstream Products

• 76011-61-5 2-(3'-benzyloxy-4',5'-dimethoxy)benzoyloxy-3,4,6-trimethoxyacetophenone 
• 143418-80-8 3-Benzyloxy-4,5-dimethoxyacetophenone 
• 901125-43-7 (-)-(2R,3R)-cis-5,7-bis(benzyloxy)-2-[3',5'-bis(benzyloxy)-4'-methoxyphenyl]chroman-3-yl 3''-benzyloxy-4'',5''-dimethoxybenzoate 
• 901125-30-2 (-)-(2R,3R)-cis-5,7-bis(benzyloxy)-2-[3',4'-bis(benzyloxy)-phenyl]chroman-3-yl 3''-benzyloxy-4'',5''-dimethoxybenzoate 
• 1027080-33-6 [1-(3-Benzyloxy-4,5-dimethoxy-phenyl)-vinyloxy]-trimethyl-silane 
• 180900-57-6 1,4-Bis-(3-benzyloxy-4,5-dimethoxy-phenyl)-butane-1,4-dione 
• 180900-29-2 2-(3-Benzyloxy-4,5-dimethoxy-benzoyl)-4-oxo-4-(3,4,5-trimethoxy-phenyl)-butyric acid ethyl ester 
• 1006689-73-1 C₂₆H₂₆O₈ 
• 1176026-91-7 (3-benzyloxy-4,5-dimethoxyphenyl)-(6-methoxy-1H-indol-3-yl)methanone 
• 76025-23-5 5,3'-diacetoxy-7,8,4',5'-tetramethoxyflavone 
• 76011-62-6 2-hydroxy-3'-benzyloxy-3,4,6,4',5'-pentamethoxy-dibenzoylmethane 
• 76011-63-7 3'-benzyloxy-5,7,8,4',5'-pentamethoxyflavone 
• 76011-64-8 3'-hydroxy-5,7,8,4',5'-pentamethoxyflavone 
• 63529-08-8 5,3'-dihydroxy-7,8,4',5'-tetramethoxyflavone 

Relevant academic research and scientific papers

Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach

BPR0L075 (2) is a potential anticancer drug candidate designed from Combretastatin A-4 (1) based on the bioisosterismprinciple.Metabolites of 2, proposed from in vitrohumanmicrosome studies,were synthesized, leading to the identification of metabolite-der

Synthesis and antiproliferative in-vitro activity of natural flavans and related compounds

The total synthesis of natural flavan racemates (±) 1, (±) 2 and natural flavones 3, 4 had thus been achieved. A straightforward synthetic procedure of flavans via the Pd-C catalyzed hydrogenation/hydrogenolysis of corresponding flavones was developed. Furthermore, the antiproliferative activities of racemic flavans (±) 1, (±) 2, flavones 3, 4, and five synthetic intermediates toward human SGC-7901, BEL-7402, HeLa, and HL-60 cell lines in vitro were evaluated by MTT assay, and the racemic flavans (±) 1 were found to have significant antiproliferative activity against all four cell lines.

Regiospecific and enantioselective synthesis of methylated metabolites of tea catechins

The regiospecific and enantioselective syntheses of various methylated regioisomers of epicatechin gallate (EGC) and epigallocatechin gallate (EGCG) have been achieved.

Synthesis and PAF antagonist activity of some 2,5-diaryltetrahydrofurans incorporating PAF-like functional groups

This paper describes the synthesis and structure-activity relationships of a series of 2,5-diaryltetrahydrofurans, as specific and potent antagonists at the rabbit washed platelet activating factor (PAF) receptor. The methoxyl groups in the known PAF antagonist L-652,731 were replaced with functional groups present in PAF and in the 'PAF-like' antagonists. Activity was generally retained or enhanced when one aryl ring in L-652,731 was elaborated; however incorporation of these functional groups into both of the aryl rings greatly reduced or abolished activity. These results are discussed in relation to a putative model for the PAF receptor.