50652-78-3

Usage

Uses

Used in Food and Beverage Industry:
METHYL 4-METHYL-2-PENTENOATE is used as a flavoring agent for adding a sweet and fruity flavor to a variety of products such as candies, beverages, and baked goods. Its ability to enhance the taste profile of these products makes it a valuable ingredient in this industry.
Used in Perfume and Fragrance Industry:
METHYL 4-METHYL-2-PENTENOATE is utilized as a component in perfumes and fragrances due to its pleasant aroma. Its distinctive scent contributes to the creation of various olfactory compositions, making it an essential part of this industry.
Used in Industrial Processes:
METHYL 4-METHYL-2-PENTENOATE also serves as a solvent in some industrial applications. Its solvent properties are harnessed in specific processes where its chemical stability and compatibility make it suitable for use.

InChI:InChI=1/C7H12O2/c1-6(2)4-5-7(8)9-3/h4-6H,1-3H3/b5-4+

Upstream product

• 78-84-2 isobutyraldehyde 
• 273201-11-9 methyl bis(2,6-dichlorophenyl)phosphonoacetate 
• 273201-10-8 methyl bis(2,6-difluorophenyl)phosphonoacetate 
• 116-54-1 dichloroacetic acid methyl ester 
• 67-56-1 methanol 
• 10321-71-8 4-methyl-pent-2-enoic acid 
• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 

Downstream Products

• 42558-54-3 Methyl 4-methyl-3-oxopentanoate 
• 1236003-36-3 methyl (3R,αS)-3-[N-tert-butyldimethylsilyloxy-N-(α-methylbenzyl)amino]-4-methylpentanoate 
• 1217531-78-6 N-tert-butoxycarbonyl-β-(R)-hydroxy-D-leucine 
• 461019-79-4 (3R)-1-butyl-2,5-dioxo-3-((1R)-1-hydroxy-2-methylpropyl)-9-benzyl-1,4,9-triazaspiro[5.5]undecane 
• 5362-55-0 4-methylpent-2-en-1-ol 
• 81569-25-7 methyl 2-amino-5-isopropyl-1,3-thiazole-4-carboxylate 

Relevant academic research and scientific papers

Formal Aza-Wacker Cyclization by Tandem Electrochemical Oxidation and Copper Catalysis

In oxidative electrochemical organic synthesis, radical intermediates are often oxidized to cations on the way to final product formation. Herein, we describe an approach to transform electrochemically generated organic radical intermediates into neutral

Discovery of 4-[4-({(3R)-1-butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-2,5- dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]benzoic acid hydrochloride: A highly potent orally available CCR5 selective antagonist

Based on the original spirodiketopiperazine design framework, further optimization of an orally available CCR5 antagonist was undertaken. Structural hybridization of the hydroxylated analog 4 derived from one of the oxidative metabolites and the new orally available non-hydroxylated benzoic acid analog 5 resulted in another potent orally available CCR5 antagonist 6a as a clinical candidate. Full details of a structure-activity relationship (SAR) study and ADME properties are presented.

Acylaminothiazole derivatives, preparation and therapeutic use thereof

This invention discloses and claims a compound conforming to the general formula (I): Wherein R1, R2, R′2, R3, R4 and R5 are as described herein. The compounds of the present invention exhibit an inhibitory effect on the production of β-amyloid peptide (β-A4) by inhibition of gamma protease. Therefore, the compounds of the present invention are useful in the treatment of pathologies such as senile dementia, Alzheimer's disease, Down's syndrome, Parkinson's disease, amyloid angiopathy and/or cerebrovascular disorders.

A study on the Z-selective Horner-Wadsworth-Emmons (HWE) reaction of methyl diarylphosphonoacetates

Experimental and theoretical studies were conducted to explore the Z-selectivities in the Horner-Wadsworth-Emmons (HWE) reaction employing several methyl diarylphosphonoacetates (3, 4, 5 and 6) and aldehydes. The Z-selectivity depended upon the reaction conditions such as the bases, reaction temperature, and the aromatic substituents on the phosphorus atoms but the almost phosphonoacetates used in the present study showed Z-selectivity in the reactions with both aromatic and aliphatic aldehydes. While the phosphonoacetate (3) with bis(2,4-difluorophenyl)phosphono group showed the highest Z-selectivity in all reaction conditions employed, decrease of the selectivity was observed in the case of some phosphonoacetates with diarylphosphono groups. These experimental results and the theoretical studies calculated by AM1 or 3-21G* ab initio methods suggested that the steric effect in the transition states of the addition steps was important rather than the electronic effect. A different aspect of the reaction courses between the Wittig and HWE reactions in the present computational chemistry was also described.