507-28-8 Usage
Chemical Properties
crystalline solid
Uses
Cation exchange reagent. Used to prepare arsonium amide, oxime, and carbohydrate derivatives.
Safety Profile
Poison by intravenous route. When heated to decomposition it emits toxic fumes of As and Cl-.
Purification Methods
A neutralised aqueous solution is evaporated to dryness. The residue is extracted into absolute EtOH, evaporated to a small volume and precipitated by addition of absolute Et2O. It is again dissolved in a small volume of absolute EtOH or ethyl acetate and re-precipitated with Et2O. Alternatively, it is purified by adding conc HCl to precipitate the chloride dihydrate. Redissolve in water, neutralise with Na2CO3 and evaporate to dryness. The residue is extracted with CHCl3 and finally crystallised from CH2Cl2 or EtOH by adding Et2O. If the aqueous layer is somewhat turbid treat. it with Celite and filter through filter paper. It can be dehydrated before use in a vacuum. The tetrafluoroborate salt has m 293-295o (needles from MeCN), and the picrate salt has m 203-204o (from EtOH). [Blicke et al. J Am Chem Soc 57 702 1935, Duke & Brown J Am Chem Soc 76 1443 1954, Popov & Humphrey J Am Chem Soc 81 2043 1959, Singhal & Raj Synth Inorg Met-org Chem 23 1011 1993, Beilstein 16 III 1006, 16 IV 1170.] POISONOUS.
Check Digit Verification of cas no
The CAS Registry Mumber 507-28-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,0 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 507-28:
(5*5)+(4*0)+(3*7)+(2*2)+(1*8)=58
58 % 10 = 8
So 507-28-8 is a valid CAS Registry Number.
InChI:InChI=1/C24H20As.ClH/c1-5-13-21(14-6-1)25(22-15-7-2-8-16-22,23-17-9-3-10-18-23)24-19-11-4-12-20-24;/h1-20H;1H
507-28-8Relevant articles and documents
Synthesis, characterization and DFT studies of electron-rich iridium(I) carbonyl complexes of an unsymmetrical phosphine–phosphine monoselenide ligand and their reactivity towards alkyl halides
Guha, Ankur Kanti,Nath, Jayashree,Saikia, Lakshi,Sarmah, Bhaskar Jyoti
, (2020/01/21)
A series of halocarbonyliridium(I) complexes of the type [Ir(CO)(P ~ Se)2X] (1) {where P-Se = 1,2-bis(diphenylphosphinomethaneselenide); X = Cl (1a), Br (1b), I (1c)} have been synthesized by the reaction of [Ir(CO)2X2]? with the ligand Ph2PCH2P(Se)Ph2. The complexes exhibit a single ν (CO) band in the region 1926 cm?1 which is significantly lower in frequency compared to Vaska's complex, trans-[Ir(CO)Cl(PPh3)2] (1965 cm?1), and substantiate the enhanced electron density at the metal centre. The complexes undergo oxidative addition (OA) reactions with electrophiles like CH3I and C2H5I to form Ir(III) alkyl species like [Ir(CO)R(P ~ Se)2IX]; [R = CH3 (2), C2H5 (3)] which exhibit ν (CO) bands in the region of 2070 cm?1. Kinetic measurements for the CH3I oxidative addition with complex 1a indicate a first order reaction. The complexes have been characterized by elemental analyses, IR and NMR spectroscopy. Density functional calculations reveal that the activation barrier for the OA is the lowest with 1a, which is also in tune with the experimental observations.
