50707-39-6Relevant articles and documents
Catalytic Asymmetric [3 + 2] Annulation of Hantzsch Esters with Racemic N-Sulfonylaziridines
Chai, Zhuo,Ma, Chen-Xue,Yang, Gaosheng,Yang, Pei-Jun,Zhu, Guo-Sheng
supporting information, p. 7933 - 7937 (2021/10/25)
Hantzsch esters (HEs) served as two-carbon partners in a copper(I)-catalyzed enantioselective [3 + 2] annulation with racemic 2-(hetero)aryl-N-sulfonyl aziridines via kinetic resolution to provide pyrrolo[2,3-b]tetrahydropyridines containing multiple contiguous stereogenic centers including all-carbon quaternary centers in excellent yields and enantiopurities and moderate-to-excellent diastereoselectivities. Mainly dependent upon the structures of the aziridines, a competitive hydrogenolysis process with HEs as the hydrogen source was also observed in some cases.
Copper iodide-catalyzed aziridination of alkenes with sulfonamides and sulfamate esters
Chang, Joyce Wei Wei,Ton, Thi My Uyen,Zhang, Zhengyang,Xu, Yanjun,Chan, Philip Wai Hong
scheme or table, p. 161 - 164 (2009/04/14)
An efficient copper iodide-catalyzed aziridination of a variety of alkenes with sulfonamides and sulfamate esters as the nitrogen source and iodosylbenzene (PhI{double bond, long}O) as the oxidant is reported herein. The reaction is operationally straight
N-CYCLIC SULFONAMIDO INHIBITORS OF GAMMA SECRETASE
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Page/Page column 56, (2010/02/14)
The invention provides N-cyclic sulfonamido compounds for use in treating or preventing cognitive disorders, such as Alzheimer’s Disease. Compounds of particular interest are defined by Formula (I), wherein R4, R5, R6, Rs
