50745-74-9Relevant academic research and scientific papers
Tandem Aldol-Cyclization Sequence for the Construction of Cyclic Ethers. The Formation of Substituted Tetrahydrofurans
Galatsis, Paul,Millan, Scott D.,Nechala, Patrik,Ferguson, George
, p. 6643 - 6651 (1994)
The application of a tandem deconjugative aldol-cyclization sequence for the construction of substituted tetrahydrofurans was examined.The aldol condensation of alkenoates proceeded with alkylation at the α-position to generate homoallylic alcohol moietie
Samarium (II) iodide-induced intermolecular coupling of a,b-unsaturated esters with ketones: Reactions of methyl propiolate and ethyl buta-2,3-dienoate with cyclohexanone and its application to synthesis of a terpene carboxylic acid
Sono, Masakazu,Doi, Natsuki,Yoshino, Eri,Onishi, Sachiko,Fujii, Daiki,Tori, Motoo
supporting information, p. 1947 - 1950 (2013/04/10)
The reactions of methyl propiolate and ethyl buta-2,3-dienoate with cyclohexanone induced by SmI2 occurred either at a- or b-position to yield different products depending on with or without a proton source. The synthesis of terpenic acid was demonstrated using this reaction.
