Tandem Aldol-Cyclization Sequence for the Construction of Cyclic Ethers. The Formation of Substituted Tetrahydrofurans

DOI: 10.1021/jo00101a024

Source and publish data:

Journal of Organic Chemistry p. 6643 - 6651 (1994)

Update date:2022-08-16

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Authors:

Galatsis, Paul

Millan, Scott D.

Nechala, Patrik

Ferguson, George

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Article abstract of DOI:10.1021/jo00101a024

The application of a tandem deconjugative aldol-cyclization sequence for the construction of substituted tetrahydrofurans was examined.The aldol condensation of alkenoates proceeded with alkylation at the α-position to generate homoallylic alcohol moietie

Full text of DOI:10.1021/jo00101a024

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