50777-64-5

Basic information

• Product Name: 2-(2-BROMOPHENYL)-2-METHYL-1,3-DIOXOLANE
• Synonyms: 2-(2-BROMOPHENYL)-2-METHYL-1,3-DIOXOLANE
• CAS NO: 50777-64-5
• Molecular Formula: C₁₀H₁₁BrO₂
• Molecular Weight: 243.099
• Mol File: 50777-64-5.mol
• Article Data: 27

Chemical Properties

• Boiling Point: 293.8°C at 760 mmHg
• Flash Point: 129.5°C
• Appearance: /
• Density: 1.433g/cm³
• Vapor Pressure: 0.00296mmHg at 25°C
• Refractive Index: 1.547
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(2-BROMOPHENYL)-2-METHYL-1,3-DIOXOLANE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-BROMOPHENYL)-2-METHYL-1,3-DIOXOLANE(50777-64-5)
• EPA Substance Registry System: 2-(2-BROMOPHENYL)-2-METHYL-1,3-DIOXOLANE(50777-64-5)

Safety Data

• Hazardous Substances Data: 50777-64-5(Hazardous Substances Data)

Usage

General Description

2-(2-Bromophenyl)-2-methyl-1,3-dioxolane is a chemical compound with the molecular formula C9H9BrO2. It is a halogenated organic compound that contains a bromine atom and a dioxolane ring. 2-(2-BROMOPHENYL)-2-METHYL-1,3-DIOXOLANE is used in organic synthesis and as a building block for the production of various pharmaceuticals and agrochemicals. It has also been studied for its potential use in materials science and as a precursor for the synthesis of various functionalized organic compounds. However, it is important to handle this compound with caution, as it may be hazardous if not handled properly.

InChI:InChI=1/C10H11BrO2/c1-10(12-6-7-13-10)8-4-2-3-5-9(8)11/h2-5H,6-7H2,1H3

Upstream product

• 2142-69-0 2-bromophenyl methyl ketone 
• 107-21-1 ethylene glycol 

Downstream Products

• 156335-55-6 N-(1,1-dimethylethyl)-3-(2-methyl-1,3-dioxolan-2-yl)benzenamine 
• 50778-03-5 [2-(2-methyl-1,3-dioxolan-2-yl)phenyl]diphenylphosphine 
• 877129-21-0 3-(2-(diphenylphosphino)phenyl)-1H-pyrazole 
• 884541-07-5 (E)-[2-((3'-N,N-dimethylamino)prop-2'-en-1'-onyl)phenyl]diphenylphosphine 
• 50777-63-4 1-(2-(diphenylphosphanyl)phenyl)ethan-1-one 
• 221187-50-4 2’-(dicyclohexylphosphino)acetophenone ethylene ketal 
• 1401549-17-4 [D₁]-acetophenone 
• 189816-06-6 3-Phenyl-isoquinoline-1-carbaldehyde 

Relevant articles and documents

Copper-Catalyzed Tandem Cross-Coupling and Alkynylogous Aldol Reaction: Access to Chiral Exocyclic α-Allenols

An enantioselective copper-catalyzed tandem cross-coupling/alkynylogous aldol reaction has been developed. The tetrasubstituted allenoates containing both central and axial chirality have been obtained in moderate to good yields and excellent enantio-and

Mechanistic Interrogation of Alkyne Hydroarylations Catalyzed by Highly Reduced, Single-Component Cobalt Complexes

Highly reactive catalysts for ortho-hydroarylations of alkynes have previously been reported to result from activation of CoBr2 by Grignard reagents, but the operative mechanism and identity of the active cobalt species have been undefined. A mechanistic analysis of a related system, involving hydroarylations of a (N-aryl)aryl ethanimine with diphenylacetylene, was performed using isolable reduced Co complexes. Studies of the stoichiometric reaction of Co(I) or Co(II) precursors with CyMgCl implicated catalyst initiation via a β-H elimination/deprotonation pathway. The resulting single-component Co(-I) complex is proposed as the direct pre-catalyst. Michaelis-Menten enzyme kinetic studies provide mechanistic details regarding the catalytic dependence on substrate. The (N-aryl)aryl ethanimine substrate exhibited saturation-like behavior, whereas alkyne demonstrated a complex dependency; rate inhibition and promotion depend on the relative concentration of alkyne to imine. Activation of the aryl C-H bond occurred only in the presence of coordinated alkyne, which suggests operation of a concerted metalation-deprotonation (CMD) mechanism. Small primary isotope effects are consistent with a rate-determining C-H cleavage. Off-cycle olefin isomerization catalyzed by the same Co(-I) active species appears to be responsible for the observed Z-selectivity.

Structural Dynamics and Stereoselectivity of Chiral Benzylideneamine N,C-Chelate Borane Photo–Thermal Isomerization

New chiral N,C-chelate organoboron compounds based on benzylideneamines (bza) with the general formula of B(bza-R)Mes2 (R=H or Me; Mes=mesityl) are reported. A chiral substituent group R- or S-CH(CH3)Ph (Ph=phenyl) was introduced to