50819-67-5

Basic information

• Product Name: O-cholesteryl p-methoxythiobenzoate
• Synonyms: O-cholesteryl p-methoxythiobenzoate
• CAS NO: 50819-67-5
• Molecular Weight: 536.863
• Mol File: 50819-67-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: O-cholesteryl p-methoxythiobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: O-cholesteryl p-methoxythiobenzoate(50819-67-5)
• EPA Substance Registry System: O-cholesteryl p-methoxythiobenzoate(50819-67-5)

Safety Data

• Hazardous Substances Data: 50819-67-5(Hazardous Substances Data)

Upstream product

• 75-44-5 phosgene 
• 57700-94-4 N-(p-methoxybenzoyl)piperidine 
• 57-88-5 cholesterol 

Relevant articles and documents

Process for deoxygenating secondary alcohols

The process for removing a secondary hydroxyl group from an organic compound having at least one secondary hydroxyl group and having any amino groups protected, comprises the reaction of a reactive ester of said secondary hydroxyl group selected from the group consisting of an O-alkylthioester and an O-alkylselenoester with at least one mole of an organotin hydride, preferably tri-n-butylstannane, in an inert, aprotic solvent at a temperature of at least about 100° C and under an inert atmosphere. The process is particularly useful in removing secondary alcohols in aminoglycoside antibiotics to produce deoxy derivatives thereof having antibacterial activity. Also described are novel O-sec.-alkylthiobenzoate, O-sec.-alkyl-S-methylxanthate, N-(sec.-alkoxythiocarbonyl)-imidazole esters, and di-O-alkylthiocarbonates having at least one secondary O-alkyl group, useful intermediates of the claimed process.