50841-46-8

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 3,5-bis(benzyloxy)benzoate is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs. Its chemical properties make it a valuable component in the creation of various medicinal compounds.
Used in Fragrance Industry:
In the fragrance industry, ethyl 3,5-bis(benzyloxy)benzoate is used as a raw material for creating scented compounds due to its pleasant odor. It plays a role in formulating perfumes and other fragranced products.
Used as Antifungal and Antimicrobial Agent:
Ethyl 3,5-bis(benzyloxy)benzoate is utilized as an antifungal and antimicrobial agent in various applications, including in the development of preservatives for pharmaceuticals and cosmetics, as well as in other industries where controlling microbial growth is essential.
Used in Chemical Reactions and Processes:
ethyl 3,5-bis(benzyloxy)benzoate is employed in a range of chemical reactions and processes, particularly in the synthesis of complex organic molecules. Its reactivity and stability make it suitable for use in multiple stages of chemical production and manufacturing.

InChI:InChI=1/C23H22O4/c1-2-25-23(24)20-13-21(26-16-18-9-5-3-6-10-18)15-22(14-20)27-17-19-11-7-4-8-12-19/h3-15H,2,16-17H2,1H3

Upstream product

• 4142-98-7 ethyl 3,5-dihydroxybenzoate 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 
• 99-10-5 3,5-Dihydroxybenzoic acid 

Downstream Products

• 28917-43-3 3,5-dibenzyloxybenzoic acid 
• 702659-39-0 C₂₆H₂₄O₁₂ 
• 4142-98-7 ethyl 3,5-dihydroxybenzoate 
• 497069-12-2 ethyl 3-(benzyloxy)-5-hydroxybenzoate 
• 24131-31-5 3,5-dibenzyloxybenzyl alcohol 
• 883242-47-5 1-(3,5-bis-benzyloxyphenyl)-3-(2,4-dihydroxyphenyl)propane-1,3-dione 
• 883242-54-4 3',5'-dibenzyloxy-7-(2,3-epoxypropoxy)flavone 
• 883242-51-1 3',5'-dibenzyloxy-7-hydroxy-flavone 
• 1006392-15-9 (S)-3',5'-dibenzyloxy-7-(2,3-epoxy-propoxy)-flavone 
• 1006392-13-7 (R)-3',5'-dibenzyloxy-7-(2,3-epoxy-propoxy)-flavone 

Relevant academic research and scientific papers

A Cd(ii) and Zn(ii) selective naphthyl based [2]rotaxane acts as an exclusive Zn(ii) sensor upon further functionalization with pyrene

A new multi-functional [2]rotaxane, ROTX, has been synthesized via a Cu(i) catalysed azide-alkyne cycloaddition reaction between Ni(ii) templated azide terminated pseudorotaxane composed of a naphthalene based heteroditopic wheel, NaphMC, and an alkyne terminated stopper. Subsequently, ROTX has been functionalized with pyrene moieties to develop a bifluorophoric [2]rotaxane, PYROTX, having naphthalene and pyrene moieties. Detailed characterization of these two rotaxanes is performed by utilizing several techniques such as ESI-MS, (1D and 2D) NMR, UV/Vis and PL studies. Comparative metal ion sensing studies of NaphMC (a fluorophoric cyclic receptor), ROTX ([2]rotaxane with a naphthyl fluorophore) and PYROTX ([2]rotaxane having naphthyl and pyrene fluorophores) have been performed to determine the effect of dimensionality/functionalization on the metal ion selectivity. Although NaphMC fails to discriminate between metal ions, ROTX serves as a selective sensor for Zn(ii) and Cd(ii). Importantly, PYROTX shows exclusive selectivity towards Zn(ii) over various transition, alkali and alkaline earth metal ions including Cd(ii).

Flavone-based novel antidiabetic and antidyslipidemic agents

The hybrid congeners 62-90 of 6- and 7-hydroxyflavones with aminopropanol have been synthesized and evaluated for their antidiabetic activity in sucrose-challenged low-dosed streptozotocin (STZ)-induced diabetic rats and db/db mice. The optical enantiomers 70a, 70b, 90a, and 90b of two congeners 70 and 90 exhibiting consistent antidiabetic and antidyslipidemic activities were also prepared, and their antidiabetic activity results indicate its association mainly with S isomers. These compounds also lower cholesterol and TG profiles while improving high-density lipoprotein cholesterol to CHOL ratio in db/db mice. The bioavailability of compound 70 and its isomer varies between 27 and 29% whereas that of the more polar compound 90a is poor as determined in rat by oral and intraperitoneal administrations. Published 2012 by the American Chemical Society.

Synthesis of organometallic poly(dendrimer)s by macromonomer polymerization: effect of dendrimer size and structural rigidity on the polymerization efficiency

Two series of first to third generation (G1-G3) oligoether dendrimers, one hearing a shorter spacer chain (C-O) and the other having a longer spacer branch (C-C-C-O) were prepared. Both series of compounds, containing two reactive C≡CH moieties on the dendrimer surface, were used as macromonomers and copolymerized with trans-[Pt(PEt3)2Cl2] to form organometallic poly(dendrimer)s by an outer-sphere-outer-sphere connection strategy. It was found that concentration of monomer used in the polymerization, the dendrimer generation, and, most strikingly, the length of the spacer were key factors that determined the polymerization efficiency. Hence, the structurally more rigid and compact C-O linked dendrimers formed poly(dendrimer)s with a higher degree of polymerization than the structurally less rigid and more bulky C-C-C-O dendrimers. This result was due to the higher tendency to form cyclic oligomers in the latter series of compounds. In addition, the differences in the polymerization efficiency among the three generations of dendrimers could be explained by the gradual decrease of reactive functional group density on the dendrimer surface.

Invertible amphiphilic polymers

Amphiphilic monomeric compounds and corresponding homopolymers and copolymers capable of assembly and invertible configuration in introduction to and change in fluid medium.

OXY SUBSTITUTED FLAVONES AS ANTIHYPERGLYCEMIC AND ANTIDYSLIPIDEMIC AGENTS

The present invention provides novel substituted flavone derivatives which exhibit anti- hyperglycemic and antidyslipedemic activity. The invention also provides a method for controlling type ii diabetes and associated hyperlipidemic conditions in a mammal by administering compound of the present invention and compositions containing these derivatives.

Synthesis of new unsymmetrical polyarylester dendrimers

Preparation of polyarylester dendrimers containing 2-(hydroxymethyl)-1,4- butanediol and 2,2-bis(hydroxymethyl)-1,4-butanediol cores is described. These polyarylester dendrimers are unsymmetrical with respect to chain lengths and function as model systems for studying in vitro controlled drug release systems. Reaction conditions for deprotection of trichloroethyl group of the dendritic wedges have been improved.

Invertible amphiphilic homopolymers

Stimuli-responsive polymers and assemblies are viable candidates for the so-called "smart" materials. In this communication, we report a new class of amphiphilic homopolymers that forms micelle-like structures in polar solvents and inverted micelle-like structures in apolar solvents. We demonstrate that these superstructures are the result of the changes in the molecular-level conformations in the monomer. Copyright