50881-28-2

Upstream product

• 1189-71-5 isocyanate de chlorosulfonyle 
• 65-85-0 benzoic acid 

Downstream Products

• 38336-79-7 N-Benzoyl-β-aethoxyvinylsulfonamid 
• 105094-62-0 N-(Pyridin-2-ylaminosulfonyl)benzamid 
• 105094-59-5 N-(Pyrimidin-2-ylaminosulfonyl)benzamid 
• 105094-64-2 N-(5-Chlorpyridin-2-ylaminosulfonyl)benzamid 
• 105094-60-8 N-(5-Chlorpyrimidin-2-ylaminosulfonyl)benzamid 
• 105094-61-9 N-(4-Chlor-6-methylpyrimidin-2-ylaminosulfonyl)benzamid 
• 105094-63-1 N-(4,6-Dimethylpyridin-2-ylaminosulfonyl)benzamid 
• 105094-65-3 N-(4-Chlorphenylaminosulfonyl)benzamid 
• 485391-82-0 C₂₄H₂₉Cl₂N₃O₄S 
• 485391-81-9 C₂₃H₂₇Cl₂N₃O₄S 
• 100-47-0 benzonitrile 
• 103-71-9 phenyl isocyanate 
• 4559-92-6 N-phenylmorpholine-4-carboxamide 
• 105094-66-4 N-(3,5-Di-chlorphenylaminosulfonyl)benzamid 

Relevant academic research and scientific papers

The Introduction of Nitrile-Groups into Heterocycles and Concversion of Carboxylic Groups into their Corresponding Nitriles with Clorosulfonylisocyanate and Triethylamine

Addition of chlorosulfonylisocyanate (CSI) to heterocycles such as thiophene (4) or indole (15) and unsaturated systems such as dihydropyran (7) gives N-chlorosulfonylamides RCONHSO2Cl, which can be converted by equivalent amounts of triethylamine to their corresponding nitriles.Since carboxylic acids react with CSI to N-chlorosulfonylamides, subsequent treatment with triethylamine affords the corresponding nitriles, but no isocyanates as claimed by other authors.The mechanisms of the conversion of the intermediate N-chlorosulfonylamides into the corresponding nitriles are discussed.

6-Acylamino-penam-3-carboxylic acids

6-acylamino-penam-3-carboxylic acids and 7-acylamino-3-cephem-4-carboxylic acids in which the acyl group has the formula STR1 in which R1 is hydrogen, R2 is optionally substituted phenyl, thienyl or furyl or R1 and R2 together are optionally substituted cycloalkyl, and R is a radical which is linked through a carbon, oxygen, sulphur or nitrogen atom.