Welcome to LookChem.com Sign In|Join Free
  • or
Isocodeine, a semi-synthetic opioid analgesic, is derived from thebaine, an alkaloid found in the opium poppy. It is structurally similar to codeine and is used to treat moderate to severe pain. Isocodeine is known for its cough-suppressing properties and is sometimes combined with other medications to form antitussive preparations. As with other opioids, it carries the risk of dependence, addiction, and side effects such as drowsiness, constipation, and respiratory depression. Its use is regulated due to its potential for abuse and the need for careful medical supervision.

509-64-8

509-64-8 Suppliers

This product is a nationally controlled contraband or patented product, and the Lookchem platform doesn't provide relevant sales information.

509-64-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 509-64-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,0 and 9 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 509-64:
(5*5)+(4*0)+(3*9)+(2*6)+(1*4)=68
68 % 10 = 8
So 509-64-8 is a valid CAS Registry Number.

509-64-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name Isocodeine

1.2 Other means of identification

Product number -
Other names C.I.Mordantbrown33

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:509-64-8 SDS

509-64-8Relevant academic research and scientific papers

A total synthesis of (±)-codeine by 1,3-dipolar cycloaddition

Erhard, Thomas,Ehrlich, Gunnar,Metz, Peter

supporting information; experimental part, p. 3892 - 3894 (2011/06/24)

Nitrone cycloaddition on a dearomatized bicyclic phenol enabled the facile construction of the correctly configured phenanthrene skeleton of codeine. Further steps yielded allopseudocodeine in a completely diastereoselective manner and finally (±)-codeine by allylic transposition through the hydrolysis of chlorocodides.

SYNTHESIS OF MORPHINE AND RELATED DERIVATIVES

-

Page/Page column 84-85, (2010/12/17)

The present invention relates to methods for the synthesis of galanthamine, morphine, intermediates, salts and derivatives thereof, wherein the starting compound is biphenyl.

Claisen Reactions on Codeins. 8-Alkyl-8,14-dihydro-6-demethoxythebaines and -oripavines

Fleischhacker, Wilhelm,Richter, Bernd

, p. 3866 - 3880 (2007/10/02)

Claisen Eschenmoser reaction of 1a leads to 2a, which is transformed to 2c, e, and f by especially adopted reduction conditions.Reduction of 2i with LiAlH4 gives 2g.Catalytic hydrogenation of 2 results in ether bridge opening and formation of 4.Reaction of 2e with 4 N HCl yields the cyclic phenol 7a.Orthoester Claisen rearrangement of 1a leads to orthoacetate 10 and 11.Claisen Eschenmoser reaction on codeine isomers 1b and 12c gives the amides 12a and 1f.

Process for converting neopinone to codeinone

-

, (2008/06/13)

A process for converting neopinone alkaloid to codeinone alkaloid which involves treating neopinone with a hydrohalic acid in a suitable solvent under anhydrous conditions. It also relates to the compound 8-halodihydrocodeinone hydrohalide.