50907-68-1

Basic information

• Product Name: (trimethylsilyl)ketene acetal of dibenzyl malonate
• Synonyms: (trimethylsilyl)ketene acetal of dibenzyl malonate
• CAS NO: 50907-68-1
• Molecular Weight: 356.494
• Mol File: 50907-68-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (trimethylsilyl)ketene acetal of dibenzyl malonate(CAS DataBase Reference)
• NIST Chemistry Reference: (trimethylsilyl)ketene acetal of dibenzyl malonate(50907-68-1)
• EPA Substance Registry System: (trimethylsilyl)ketene acetal of dibenzyl malonate(50907-68-1)

Safety Data

• Hazardous Substances Data: 50907-68-1(Hazardous Substances Data)

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 15014-25-2 malonic acid dibenzyl ester 

Downstream Products

• 111934-08-8 (3S,5S,6R)-4-<(benzyloxy)carbonyl>-3-(O,O'-dibenzylmalonyl)-5,6-diphenyl-2,3,5,6-tetrahydro-2H-1,4-oxazin-2-one 
• 111934-07-7 (3R,5S,6R)-4-<(benzyloxy)carbonyl>-3-(O,O'-dibenzylmalonyl)-5,6-diphenyl-2,3,5,6-tetrahydro-2H-1,4-oxazin-2-one 

Relevant articles and documents

Asymmetric Synthesis of β-Carboxyaspartic Acid

Bromoglycinate 4 was coupled with the (trimethylsilyl)ketene acetal of dibenzyl malonate to furnish predominantly the syn-lactone 6.Hydrogenolysis of 6 directly afforded β carboxyaspartic acid (Asa) in 30percent overall yield in >98percent ee.The optical purity of the synthetic Asa was determined by decarboxylation and esterification to aspartic acid diethyl eester.