50916-35-3Relevant academic research and scientific papers
Acylation of aryl halides and α-bromo acetates with aldehydes enabled by nickel/tbadt cocatalysis
Fan, Pei,Zhang, Chang,Zhang, Linchuan,Wang, Chuan
supporting information, p. 3875 - 3878 (2020/05/14)
In this protocol aryl halides and α-bromo acetates are efficiently cross-coupled with an array of (hetero)aromatic and aliphatic aldehydes under the cooperative catalysis of nickel and tetrabutylammonium decatungstate as a hydrogen-atom-transfer photocatalyst. This method provides a concise approach to a variety of ketones with high compatibility of various functional groups.
Copper-Catalyzed Enantioselective Alkylation of Enolizable Ketimines with Organomagnesium Reagents
Ortiz, Pablo,Collados, Juan F.,Jumde, Ravindra P.,Otten, Edwin,Harutyunyan, Syuzanna R.
supporting information, p. 3041 - 3044 (2017/03/14)
Inexpensive and readily available organomagnesium reagents were used for the catalytic enantioselective alkylation of enolizable N-sulfonyl ketimines. The low reactivity and competing enolization of the ketimines was overcome by the use of a copper–phosphine chiral catalyst, which also rendered the transformation highly chemoselective and enantioselective for a broad range of ketimine substrates.
Barbier-type reactions of nitriles and alkyl iodides mediated by samarium(II) iodide in the presence of catalytic nickel(II) iodide
Kang, Han-Young,Song, Sang-Eun
, p. 937 - 939 (2007/10/03)
The samarium(II) iodide-mediated intermolecular Barbier-type reactions of nitriles and alkyl iodides have been investigated. In the presence of a catalytic amount of nickel(II) iodide, the reaction proceeded smoothly to provide the corresponding ketones. Amides also reacted to give ketones under the same Barbier-type conditions. (C) 2000 Elsevier Science Ltd.
3' Cyanophenylalkanolamines: a contribution to the search for selective β adrenomimetic compounds
Pratesi,Grana,Villa
, p. 753 - 765 (2007/10/06)
Some derivatives of 1 (3' cyanophenyl) 2 aminoethanol have been synthesized in which OH is substituted at the nucleus, methyl or ethyl at the α carbon atom and isopropyl or t butyl at the nitrogen atom. The pharmacological research has shown that by combi
