50917-84-5Relevant academic research and scientific papers
On the stereochemical purity of (+)-7-aminocephalosporanic acid
Oberhauser, Thomas,Meduna, Vladimir
, p. 7691 - 7702 (1996)
(±)-7-Aminocephalosporanic acid (18a) and (±)-7-epi- aminocephalosporanic acid (4a) have been synthesized. A chiral HPLC method has been developed for the separation of the four stereo-isomers. Natural (+)-7-aminocephalosporanic acid (1) was demonstrated to he enantiomerically (ee >> 99.95%) and diastereomerically (de >>99.95%) pure.
Cephalosporin compounds
-
, (2008/06/13)
Novel 7-azido-3-cephem compounds are prepared via α-amino-phosphonoacetate esters. The cephem compounds are intermediates for the preparation of novel and known useful antibiotic cephalosporins.
