5094-24-6

Basic information

• Product Name: SODIUM 2-HYDROXYBUTYRATE
• Synonyms: DL-2-HYDROXYBUTYRIC ACID SODIUM SALT;DL-2-HYDROXY-N-BUTYRIC ACID SODIUM SALT;(+/-)-2-HYDROXYBUTANOIC ACID SODIUM SALT;2-HYDROXYBUTYRIC ACID SODIUM SALT;SODIUM 2-HYDROXYBUTYRATE;SODIUM DL-2-HYDROXY-N-BUTYRATE;DL-2-Hydroxybutyricacidsodiumsalt,98%;2-HYDROXYBUTYRIC ACID SODIUM SALT 98%
• CAS NO: 5094-24-6
• Molecular Formula: C₄H₇O₃*Na
• Molecular Weight: 126.09
• EINECS: 225-812-4
• Product Categories: Carbonyl Compounds;Carboxylic Acid Salts;Organic Building Blocks
• Mol File: 5094-24-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 133-135 °C(lit.)
• Boiling Point: 108℃
• Flash Point: 112.2 °C
• Appearance: /
• Density: 1.195g/cm3
• Vapor Pressure: 0.00759mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: Methanol (Slightly), Water (Slightly)
• Water Solubility: almost transparency
• Sensitive: Hygroscopic
• Stability: Hygroscopic
• BRN: 4825104
• CAS DataBase Reference: SODIUM 2-HYDROXYBUTYRATE(CAS DataBase Reference)
• NIST Chemistry Reference: SODIUM 2-HYDROXYBUTYRATE(5094-24-6)
• EPA Substance Registry System: SODIUM 2-HYDROXYBUTYRATE(5094-24-6)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 3
• Hazardous Substances Data: 5094-24-6(Hazardous Substances Data)

Usage

Application

2-Hydroxybutyric acid sodium salt was used in gas chromatographic (GC) method for the indirect enantioresolution of 2- and 3-hydroxy fatty acids.

Uses

Sodium 2-Hydroxybutyrate is used to prepare (D)-β-Hydroxybutyrate, which inhibits adipocyte lipolysis, in a pharmacological study.

InChI:InChI=1/C4H8O3/c1-2-3(5)4(6)7/h3,5H,2H2,1H3,(H,6,7)/p-1/t3-/m1/s1

Upstream product

• 2013-26-5 2-oxobutyric acid, sodium salt 
• 3347-90-8 (2S)-2-hydroxybutanoic acid 

Downstream Products

• 130516-25-5 Benzyl 2-hydroxybutanoate 
• 41358-69-4 triethyl 2-oxa-1,3,3-butanetricarboxylate 
• 132513-51-0 n-butyl (S)-2-hydroxybutanoate 
• 600-15-7 2-Hydroxybutanoic acid 
• 110298-82-3 2-Benzyloxy-butyric acid benzyl ester 

Relevant articles and documents

Method for Improving Optical Purity of 2-Hydroxycarboxylic Acid or Derivative Thereof

To provide a method for improving optical purity of an optically active 2-hydroxycarboxylic acid or a derivative thereof, which is useful as a raw material in the manufacture of medicines, agrochemicais, and industrial products. The method of the invention for improving purity of a hydroxycarboxylic acid of the following formula (1a) or (1b) or a derivative thereof includes the steps of reacting the hydroxycarboxylic acid of the following formula (1a) or (1b) with at least one optically inactive base selected from the group consisting of an alkali metal, alkoxide and a secondary amine in the presence of a solvent and, subsequently, performing recrystallization, to thereby form a hydroxycarboxylic acid salt of the following formula (IIIa) or (IIIb): wherein R1 represents a C1-8 alkyl group, and R2 represents an alkali metal or a secondary amine.