50984-10-6Relevant academic research and scientific papers
Synthesis of enantiopure 1-r-alkyl-2-c,5-t-diphenylphospholanes and phospholanium salts through direct alkylation of phospholane
Dobrota, Cristian,Duraud, Amelie,Toffano, Martial,Fiaud, Jean-Claude
body text, p. 2439 - 2445 (2009/04/10)
Chiral enantiopure 1-alkyl-2,5-diphenylphospholanium salts were obtained in one step through alkylation of phospholane with alkyl triflates. The resulting air-stable phosphonium salts are electron-rich trialkylphosphane precursor ligands for transition metals, and they offer a convenient route toward chiral quaternary phosphonium salts as phase-transfer agents. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
A new method for constructing quaternary carbon centres: Tandem rhodium-catalysed 1,4-addition/intramolecular cyclisation
Le Notre, Jerome,Van Mele, David,Frost, Christopher G.
, p. 432 - 440 (2008/02/07)
The efficient tandem rhodium-catalysed 1,4-addition/cyclisation of 1,1′-alkenes using arylzinc chlorides is described. The simple one-step synthesis of substituted cyclopentanone and cyclohexanone derivatives is performed from acyclic precursors using relatively low catalyst loadings under mild conditions. A new quaternary carbon centre is created during the cyclisation step.
