20270-53-5

Basic information

• Product Name: Hexanedioic acid, bis(1,1-diMethylethyl) ester
• Synonyms: Hexanedioic acid, bis(1,1-diMethylethyl) ester
• CAS NO: 20270-53-5
• Molecular Formula: C₁₄H₂₆O₄
• Molecular Weight: 258.35384
• Mol File: 20270-53-5.mol
• Article Data: 10

Chemical Properties

• Melting Point: 32.5 °C
• Boiling Point: 134 °C
• Appearance: /
• Density: 0.968±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: Hexanedioic acid, bis(1,1-diMethylethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: Hexanedioic acid, bis(1,1-diMethylethyl) ester(20270-53-5)
• EPA Substance Registry System: Hexanedioic acid, bis(1,1-diMethylethyl) ester(20270-53-5)

Safety Data

• Hazardous Substances Data: 20270-53-5(Hazardous Substances Data)

Usage

General Description

Hexanedioic acid, bis(1,1-dimethylethyl) ester, also known as diethyl adipate, is a chemical compound commonly used as a solvent and plasticizer. It is a clear, colorless liquid with a slightly fruity odor and is insoluble in water. This chemical is primarily used in the production of perfumes and cosmetics, as well as in the manufacturing of plasticizers, resins, and dyes. It is considered a low-toxicity compound, with low potential for skin and eye irritation, and is generally regarded as safe for use in consumer products at low levels. However, prolonged or repeated exposure to high concentrations may cause irritation to the respiratory system and skin, and it is important to handle and store this chemical in accordance with proper safety protocols.

Upstream product

• 111-50-2 Adipic acid dichloride 
• 75-65-0 tert-butyl alcohol 
• 124-04-9 Adipic acid 

Downstream Products

• 40832-99-3 N-phenylazepane 
• 19858-02-7 N-Phenylhexahydroazepin-2-on 
• 1617568-30-5 (3S,4S,4aR,7aS)-tert-butyl octahydro-3-methyl-2-oxo-4-phenylcyclopenta[b]pyran-4a-carboxylate 
• 1617568-07-6 tert-butyl 1-(E)-(2-(methoxycarbonyl)-3-phenylallyl)-2-oxocyclopentane-1-carboxylate 
• 50984-10-6 tert-butyl 1-benzyl-2-oxocyclopentanecarboxylate 
• 57026-62-7 2-(Pent-2-enyl)cyclopentan-1-one 
• 30079-93-7 2-allylcyclopentanone 
• 2867-63-2 2-benzylcyclopentanone 
• 1124-13-6 (+/-)-(1S,2S)-cyclobutane-1,2-dicarboxylic acid 
• 745765-87-1 (1R,2S,3R)-3-methyl-2-aminocyclopentane carboxylic acid 
• 646518-07-2 tert-butyl 3-methyl-2-(4-methylbenzenesulfonyloxy)cyclopentane-1-carboxylate 
• 820236-40-6 tert-butyl 2-hydroxy-3-ethylcyclopentane-1-carboxylate 
• 820236-09-7 tert-butyl 3-ethyl-2-oxocyclopentane-1-carboxylate 

Relevant articles and documents

Asymmetric synthesis of (1R,2S,3R)-γ-methyl-cis-pentacin by a kinetic resolution protocol

The asymmetric synthesis of (1R,2S,3R)-3-methyl-2-aminocyclopentane carboxylic acid has been achieved via kinetic resolution of racemic tert-butyl 3-methyl-cyclopentene-1-carboxylate with homochiral lithium (S)-N-benzyl-N-α-methylbenzylamide.

Assisted Tandem Catalytic Conversion of Acrylates into Adipic Esters

A ruthenium-catalyzed tail-to-tail dimerization of acrylates followed by hydrogenation results in the synthesis of adipic esters in one pot. An imine-ligated ruthenium complex that has good catalytic reactivity for tail-to-tail dimerization of methyl acrylate can be readily converted to a hydrogenation catalyst resulting in the assisted tandem catalytic conversion of methyl acrylate to methyl adipate.

Organocatalytic enantioselective allylic alkylation of MBH carbonates with β-keto esters

The highly stereoselective allylic alkylation of Morita-Baylis-Hillman carbonates with β-ketoesters catalysed by β-ICD is described. The corresponding products containing two adjacent quaternary and tertiary carbon centers were obtained in good yields with high diastereoselectivity (up to 10 : 1 dr) and enantioselectivity (up to 95% ee).

A systematic study of the solid state and solution phase conformational preferences of β-peptides derived from transpentacin

The solid state and solution phase conformational preferences of a homologous series of β-peptides derived from (S,S)-2- aminocyclopentanecarboxylic acid (transpentacin) have been investigated using a variety of spectroscopic and crystallographic techniqu