50994-79-1Relevant academic research and scientific papers
A new diastereo- and enantioselective copper-catalyzed conversion of alkynyl epoxides into α-allenic alcohols
Bertozzi, Fabio,Crotti, Paolo,Macchia, Franco,Pineschi, Mauro,Arnold, Alexander,Feringa, Ben L.
, p. 4893 - 4896 (1999)
Chiral copper complexes of BINOL- and TADDOL derived phosphorus amidites proved to be highly effective catalysts for the alkylation of alkynyl epoxides with dialkylzinc reagents. The corresponding α-allenol reaction products (S(N)2'-pathway) were obtained
Iron-Catalyzed Cross-Coupling Reactions: Efficient Synthesis of 2, 3-Allenol Derivatives
Fuerstner, Alois,Mendez, Maria
, p. 5355 - 5357 (2003)
Reliable chirality transfer is one of the major advantages of a novel synthesis of 2,3-allenols from propargyl epoxides (see scheme) catalyzed by inexpensive and environmentally benign iron salts. The reactions proceed very rapidly in excellent yields and
