50995-48-7

Usage

Uses

Methyl 2,5-Dibromopentanoate can be used for liquid crystal compounds for display devices.

InChI:InChI=1/C6H10Br2O2/c1-10-6(9)5(8)3-2-4-7/h5H,2-4H2,1H3

Upstream product

• 542-28-9 3,4,5,6-tetrahydro-2H-pyran-2-one 
• 67-56-1 methanol 
• 2067-33-6 5-bromopentanoic acid 

Downstream Products

• 139331-33-2 2-(3-Bromo-propyl)-7-chloro-4H-benzo[1,4]thiazin-3-one 
• 139516-24-8 6,7-cyclopenteno-2-<3-<4-(4-fluorophenyl)-1-piperazinyl>propyl>-2H-1,4-benzoxazin-3(4H)-one 
• 624-24-8 methyl valerate 
• 5454-83-1 5-bromovaleric acid methyl ester 
• 765-85-5 methyl cyclobutanecarboxylate 
• 212578-37-5 6-(3-{Benzyl-[2-(3,4-dimethoxy-phenyl)-ethyl]-amino}-propyl)-2,3-dihydro-8H-1,4,5-trioxa-8-aza-anthracen-7-one 
• 1069-31-4 Ornithin-dihydrochlorid 
• 112249-82-8 methyl 5-bromo-2-(5-ethoxycarbonyl-2-nitrophenoxy)valerate 
• 112249-86-2 methyl 5-[4-(4-fluorophenyl)-1-piperazinyl]-2-(2-isopropyl-5-methyl-6-nitrophenoxy)valerate 
• 112249-91-9 methyl 5-bromo-2(5,6,7,8-tetrahydro-1-nitro-2-naphthyloxy)valerate 
• 112249-92-0 methyl 5-[4-(4-fluorophenyl)-1-piperazinyl]-2-(5,6,7,8-tetrahydro-1-nitro-2-naphthyloxy)valerate 
• 112249-89-5 methyl 5-bromo-2-(4,5-methylenedioxy-2-nitrophenoxy)valerate 
• 112249-90-8 methyl 5-<4-(4-fluorophenyl)-1-piperazinyl>-2-(4,5-methylenedioxy-2-nitrophenoxy)valerate 

Relevant academic research and scientific papers

2-(1-bromocyclobutyl) pyridine and synthesis method thereof

The invention belongs to the technical field of organic synthesis, and relates to 2- (1-bromocyclobutyl) pyridine and a synthesis method thereof. The 2 -(-1bromocyclobutyl) pyridine can be used as a medical intermediate, and the synthetic method of the compound comprises the following steps: by taking tetrahydropyrane- 2-ketone as a raw material, carrying out nine steps of reactions including substitution, ring closing, hydrolysis, substitution, substitution, reduction, grignard, substitution and substitution to prepare the 2- (-1bromocyclobutyl) pyridine, so that the synthetic route is simple, the cost is low, and the efficiency is high.

DIHYDROPYRIMIDO LOOP DERIVATIVE AS HBV INHIBITOR

Disclosed is a dihydropyrimido fused ring derivative as a HBV inhibitor, and in particular relates to a compound shown as formula (I) or a pharmaceutically acceptable salt thereof.

Chemical generation and modification of peptides containing multiple dehydroalanines

Chemical formation of dehydroalanine has been widely used for the post-translational modification of proteins and peptides, however methods to incorporate multiple dehydroalanine residues into a single peptide have not been defined. We report the use of methyl 2,5-dibromovalerate which can be used to cleanly carry out this transformation.

IMPROVED PROCESS FOR THE MANUFACTURE OF 1,2-DISUBSTITUTED HEXAHYDROPYRIDAZINE-3-CARBOXYLIC ACIDS AND ESTERS THEREOF

The invention relates to an improved process for the manufacture of 1,2-disubstituted hexahydro-pyridazine-3-carboxylic acids and esters thereof by reacting N,N’-disubstituted hydrazine with 2,5-dihalogenated valeric acids and thereof by means of phase transfer catalysis. Said pyridazine carboxylic acids and esters thereof can be used as intermediates for the production of pharmaceutical products

Azetidine based ligands in boron catalyzed asymmetric

The preparation of a new class of azetidine-based auxiliaries and their selectivity in the BBr3 catalyzed Diels-Alder reaction is described. The results are compared with a similar proline-derived ligand and a known prolinol auxiliary. Results show that selectivities are highly dependent on the dienophile and the substituent of the chiral auxiliary.