51028-96-7

Usage

InChI:InChI=1/C10H12O3/c1-7-3-8(6-10(11)12)5-9(4-7)13-2/h3-5H,6H2,1-2H3,(H,11,12)

Upstream product

• 124-38-9 carbon dioxide 
• 874-63-5 3,5-dimethylmethoxybenzene 
• 106116-42-1 1-bromomethyl-3-methoxy-5-methyl-benzene 
• 200214-25-1 2-(3-methoxy-5-methylphenyl)acetonitrile 
• 51352-18-2 methyl 2-(3-methoxy-5-methylphenyl)acetate 

Downstream Products

• 62846-20-2 2-(3-methoxy-5-methylphenyl)ethan-1-ol 
• 798566-25-3 2-(3,4-dimethoxy-phenyl)-3-[2-(3-methoxy-5-methyl-phenyl)-acetylamino]-propionic acid ethyl ester 
• 798566-26-4 6,7-dimethoxy-1-(3-methoxy-5-methyl-benzyl)-3,4-dihydro-isoquinoline-4-carboxylic acid ethyl ester 
• 798566-27-5 6,7-dimethoxy-1-(3-methoxy-5-methyl-benzyl)-isoquinoline-4-carboxylic acid ethyl ester 
• 1246923-17-0 2-(2,6-bis((E)-3-ethoxy-3-oxoprop-1-enyl)-3-methoxy-5-methylphenyl)acetic acid 
• 202655-92-3 1-[2'-(3''-methoxy-5''-methylphenyl)ethyl]-1,4-dihydrobenzoic acid 
• 202655-94-5 methyl 1-[2'-(3''-methoxy-5''-methylphenyl)ethyl]-4-oxo-1,4-dihydrobenzoate 
• 202655-93-4 methyl 1-[2'-(3''-methoxy-5''-methylphenyl)ethyl]-1,4-dihydrobenzoate 
• 202655-90-1 2-(3'-methoxy-5'-methylphenyl)ethyl methanesulfonate 
• 202655-91-2 2-(3'-methoxy-5'-methylphenyl)ethyl iodide 

Relevant academic research and scientific papers

FUSED [1,2,4]THIADIAZINE DERIVATIVES WHICH ACT AS KAT INHIBITORS OF THE MYST FAMILY

A compound of formula (I): which inhibits the activity of one or more KATs of the MYST family, i.e., TIP60, KAT6B, MOZ, HBO1 and MOF.

Controlled anion migrations with a mixed metal Li/K-TMP amide: General application to benzylic metalations

A general method is described for benzylic metalation of o-, m-, and p-substituted toluenes using a mixed metal amide base generated from BuLi/KOtBu/TMP at -78 °C in THF. The excellent selectivity achieved can be rationalized by the ability of the mixed metal amide base to facilitate an anion migration from the kinetic (o-aryl) to the benzylic metalation site. Remarkably, this controlled anion migration is achievable with catalytic amounts of TMP at -78 °C.

GFAT INHIBITORS

Compounds of formula (I) are provided as well as pharmaceutically acceptable salts and esters thereof, wherein the substituents are as disclosed in the specification. The compounds have utility for the treatment of type 2 diabetes mellitus.

AMINO ACID DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS

There is provided compounds of formula I, wherein R 1, R 2, R 3, R x, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required as in thrombosis or as anticoagulants.

Exploratory studies on the synthesis of the unusual diterpenoid tropone harringtoriolide

Various approaches to the total synthesis of the unusual diterpenoid tropone (2), discovered in the yew species Cephalotaxus harringtonia and C. hainanensis, are described. The rhodium-catalysed intramolecular cyclopropanation reaction of an ary1 ring by