51051-82-2

Usage

Molecular weight

384.47 g/mol

Appearance

Clear, colorless to pale yellow liquid

Solubility

Soluble in most organic solvents, slightly soluble in water

Boiling point

Not provided

Melting point

Not provided

Density

Not provided

Flash point

Not provided

Viscosity

Not provided

Volatile organic compound (VOC) content

Low

Uses

1. Plasticizer in polymers and resins
2. Solvent in adhesives and coatings
3. Production of pharmaceuticals and personal care products

Environmental impact

Environmentally friendly

Toxicity

Not provided

Hazardous properties

Not provided

Regulatory status

Not provided

Safety precautions

Not provided

Storage conditions

Not provided

Shelf life

Not provided

Upstream product

• 101864-30-6 O⁴-benzoyl-O¹,O²;O⁵,O⁶-diisopropylidene-D-arabino-[3]hexulose 
• 1707-77-3 1,2:5,6-di-O-isopropylidene-D-mannitol 
• 189701-50-6 (1R,2S)-2-(tert-Butyl-diphenyl-silanyloxy)-1,2-bis-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanol 
• 189701-54-0 (R)-2-(tert-Butyl-diphenyl-silanyloxy)-1,2-bis-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanone 
• 98-88-4 benzoyl chloride 
• 189701-88-0 (1S,2S)-2-(tert-Butyl-diphenyl-silanyloxy)-1,2-bis-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanol 

Downstream Products

• 83023-95-4 3⁽⁴⁾-O-benzyl-D-mannitol 
• 170874-77-8 (2R,3R,4R,5R)-4-O-Benzoyl-1,2;5,6-di-O-isopropylidene-3-O-hexane-1,2,3,4,5,6-hexol 
• 1707-77-3 1,2:5,6-di-O-isopropylidene-D-mannitol 
• 113927-35-8 O⁴-benzoyl-O¹,O²;O⁵,O⁶-diisopropylidene-D-arabino-[3]hexulose-phenylhydrazone 
• 643-03-8 D-talitol 
• 82977-07-9 3⁽⁴⁾-O-benzyl-1,6-di-O-trityl-2,4⁽³⁾,5-tri-O-p-nitrobenzoyl-D-mannitol 
• 82977-05-7 3⁽⁴⁾-O-allyl-1,6-di-O-trityl-2,4⁽³⁾,5-tri-O-p-nitrobenzoyl-D-mannitol 
• 170874-86-9 Methanesulfonic acid (1R,2S)-2-(tert-butyl-diphenyl-silanyloxy)-1,2-bis-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl ester 
• 170874-80-3 Benzoic acid (1S,3S)-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-3-hydroxy-4-(toluene-4-sulfonyloxy)-butyl ester 
• 170874-78-9 (2R,3S,5S)-3-O-Benzoyl-1,2;5,6-di-O-isopropylidenehexane-1,2,3,5,6-pentol 
• 170874-79-0 (2R,3S,5S)-3-O-Benzoyl-1,2-O-isopropylidenehexane-1,2,3,5,6-pentol 
• 94869-54-2 3-O-Benzoyl-1,2;5,6-di-O-isopropyliden-4-O-methansulfonyl-D-mannitol 
• 189701-87-9 (S)-2-(2,6-Dichloro-benzyloxy)-1,2-bis-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanone 

Relevant academic research and scientific papers

Diastereoselective Grignard Additions to O-Protected Polyhydroxylated Ketones: A Reaction Controlled by Groundstate Conformation?

The O-protected polyhydroxy ketones 9-14 and 39, 42 add σ-type Grignard reagents with >90:10 stereoselectivity to give the 3,4-syn-adducts 17-22 and 43, 45, respectively, as the major diastereomers (Tables 1 and 2). The stereoselectivity is interpreted in terms of early transition states which are very close to the groundstate conformations shown in Figure 6 and 7. These demonstrate that the "top face" of the carbonyl group is much less shielded than the "bottom" face, Complexation phenomena are of minor importance. It is also shown that the classical transition state models (Felkin-Anh or chelate Cram) are not applicable to polyoxygenated ketones.

New Chiral Building Blocks from 1,2;5,6-Di-O-isopropylidene-D-mannitol: Synthesis of C2-Symmetrical and Unsymmetrical Mono- and Bisepoxides and of a Polyhydroxylated Butenolide

The enantiopure epoxides 2-6 were synthesized from 1,2;5,6-di-O-isopropylidene-D-mannitol (1).The terminal epoxides 2 and 3 are available from the desoxy mannitol 9 in three steps.The C2-symmetrical epoxides 4 and 5 were generated via the C-4-inverted alcohol 15.The C2-symmetrical bisepoxide 6 was prepared in a short sequence maintaining the symmetry throughout the entire synthesis.The crystalline butenolide 44 was prepared in five steps from 1 by Wittig olefination and lactonization. - Key Words: Epoxides, C2-symmetrical / Bisepoxides / Butenolide, polyhydroxylated

Clavulanic Acid Biosynthesis: the Stereochemical Course of β-Lactam Formation from Chiral Glycerol

The overall stereochemical course of β-lactam formation in clavulanic acid was determined to be retention from (1R,2R)- and (1S,2R)-,glycerol.