94869-54-2

Upstream product

• 1707-77-3 1,2:5,6-di-O-isopropylidene-D-mannitol 
• 101864-30-6 O⁴-benzoyl-O¹,O²;O⁵,O⁶-diisopropylidene-D-arabino-[3]hexulose 
• 51051-82-2 O³-benzoyl-O¹,O²;O⁵,O⁶-diisopropylidene-D-mannitol 
• 98-88-4 benzoyl chloride 
• 100759-35-1 Mono-O-benzoyl-1,2;5,6-bis-O-isopropyliden-D-talit 
• 124-63-0 methanesulfonyl chloride 

Relevant academic research and scientific papers

New Chiral Building Blocks from 1,2;5,6-Di-O-isopropylidene-D-mannitol: Synthesis of C2-Symmetrical and Unsymmetrical Mono- and Bisepoxides and of a Polyhydroxylated Butenolide

The enantiopure epoxides 2-6 were synthesized from 1,2;5,6-di-O-isopropylidene-D-mannitol (1).The terminal epoxides 2 and 3 are available from the desoxy mannitol 9 in three steps.The C2-symmetrical epoxides 4 and 5 were generated via the C-4-inverted alcohol 15.The C2-symmetrical bisepoxide 6 was prepared in a short sequence maintaining the symmetry throughout the entire synthesis.The crystalline butenolide 44 was prepared in five steps from 1 by Wittig olefination and lactonization. - Key Words: Epoxides, C2-symmetrical / Bisepoxides / Butenolide, polyhydroxylated