51085-35-9

Basic information

• Product Name: 2-{3-nitroanilino}nicotinamide
• Synonyms: 2-{3-nitroanilino}nicotinamide
• CAS NO: 51085-35-9
• Molecular Formula: C₁₂H₁₀N₄O₃
• Molecular Weight: 258.2328
• Mol File: 51085-35-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-{3-nitroanilino}nicotinamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{3-nitroanilino}nicotinamide(51085-35-9)
• EPA Substance Registry System: 2-{3-nitroanilino}nicotinamide(51085-35-9)

Safety Data

• Hazardous Substances Data: 51085-35-9(Hazardous Substances Data)

Upstream product

• 99-09-2 3-nitro-aniline 
• 97510-86-6 potassium 2-chloro-nicotinate 
• 2942-59-8 2-chloronicotinic acid 
• 1336-21-6 ammonium hydroxide 
• 110546-49-1 2-(3-nitroanilino)-3-chloroformylpyridine 
• 57978-48-0 2-(m-nitrophenylamino)nicotinic acid 

Downstream Products

• 59361-55-6 1-(3-nitro-phenyl)-3,4-dihydro-1H-pyrido[2,3-d]pyrimidin-2-one 
• 59398-66-2 3-benzyl-1-(3-nitro-phenyl)-3,4-dihydro-1H-pyrido[2,3-d]pyrimidin-2-one 
• 152815-12-8 2-(3-nitroanilino)-3-aminomethylpyridine 
• 152815-26-4 1-(3-aminophenyl)-3-(pyridin-4-ylmethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 
• 152815-02-6 1-(3-nitrophenyl)-3-(pyridin-3-ylmethyl)pyrido[2,3-d]-pyrimidine-2,4(1H,3H)-dione 
• 152815-27-5 1-(3-Nitrophenyl)-3-(4-pyridyl-N-oxide-methyl)pyrido [2,3-d]pyrimidine-2,4(1H,3H)-dione 
• 152814-89-6 1-(3-nitrophenyl)-3-(4-pyridylmethyl)-1,2,3,4-tetrahydropyrido(2,3-d)pyrimidine-2,4-dione 
• 56738-76-2 1-(3-nitrophenyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 

Relevant articles and documents

Optionally substituted pyrido[2,3-d]pyridine-2,4(1H,3H)-diones and pyrido[2,]pyrimidine-2(1H,3H)-ones

The present invention relates to optionally substituted pyrido[2,3-d]pyrimidine-2,4(1H,3H)-diones or optionally substituted pyrido[2,3-d]pyrimidine-2(1H,3H)-ones, i.e., compounds of Formula I: STR1 wherein: Y is --CH2 -- or --C(O)--; R1 is hydrogen or --(CH2)n --R7, wherein: R7 is aryl or heteroaryl, and n is 1 or 2, provided that when Y is --C(O)--, R7 is heteroaryl; and R2, R3, R4, R5 and R6 are hydrogen, or one is selected from lower alkyl, halo, carboxy, methoxycarbonyl, carbamoyl, methylcarbamoyl, di-methylcarbamoyl, methylcarbonyl, methylthio, methylsulfinyl, methylsulfonyl, hydroxymethyl, amino, trifluoromethyl, cyano or nitro; or R2, R3, R4 and R5 are independently selected from hydrogen, lower alkyl, nitro, chloro, fluoro, methoxycarbonyl or methylcarbonyl, provided at least one is hydrogen, and R6 is hydrogen; or a pharmaceutically acceptable ester, ether or salt thereof.