5109-99-9Relevant academic research and scientific papers
Cytochrome P450 2C9 type II binding studies on quinoline-4-carboxamide analogues
Peng, Chi-Chi,Cape, Jonathan L.,Rushmore, Tom,Crouch, Gregory J.,Jones, Jeffrey P.
experimental part, p. 8000 - 8011 (2009/12/07)
CYP2C9 is a significant P450 protein responsible for drug metabolism. With the increased use of heterocyclic compounds in drug design, a rapid and efficient predrug screening of these potential type II binding compounds is essential to avoid adverse drug
