511274-41-2Relevant articles and documents
Synthesis and screening of bicyclic carbohydrate-based compounds: A novel type of antivirals
Van Hoof, Steven,Ruttens, Bart,Hubrecht, Idzi,Smans, Gert,Blom, Petra,Sas, Benedikt,Van Hemel, Johan,Vandenkerckhove, Jan,Van Der Eycken, Johan
, p. 1495 - 1498 (2007/10/03)
A small library of bicyclic carbohydrate derivatives was synthesized and screened. A strong and selective activity against cytomegalovirus was found. Structure-activity relationship for this new type of antivirals is discussed.
Bicyclic carbohydrate compounds useful in the treatment of infections caused by herpesviridae
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Page/Page column 4-5, (2008/06/13)
Bicyclic carbohydrates for the treatment of infections caused by herpseviridae, and in particular cytomegalovirus. The invention consists of the novel bicyclic carbohydrates the generic structure of which is: wherein R1 is either -Bn or -Ph; R2 and R3 are either -alkyl, -aryl, -allyl, or —H; R4 and R5 form a ring and are either —CH(Ph)- or —CH(aryl)- and X is either O, N or S.