51134-60-2

Basic information

• Product Name: 3-bromooctan-2-one
• Synonyms: 3-bromooctan-2-one
• CAS NO: 51134-60-2
• Molecular Formula: C₈H₁₅BrO
• Molecular Weight: 207.1081
• EINECS: 257-002-1
• Mol File: 51134-60-2.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 226.9°Cat760mmHg
• Flash Point: 32.8°C
• Appearance: /
• Density: 1.209g/cm³
• Vapor Pressure: 0.0799mmHg at 25°C
• Refractive Index: 1.459
• CAS DataBase Reference: 3-bromooctan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromooctan-2-one(51134-60-2)
• EPA Substance Registry System: 3-bromooctan-2-one(51134-60-2)

Safety Data

• Hazardous Substances Data: 51134-60-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H15BrO/c1-3-4-5-6-8(9)7(2)10/h8H,3-6H2,1-2H3

Upstream product

• 111-13-7 hexyl-methyl-ketone 
• 108-22-5 Isopropenyl acetate 
• 7726-95-6 bromine 
• 56-23-5 tetrachloromethane 
• 67810-87-1 2-Octyl benzyl ether 
• 4128-31-8 rac-octan-2-ol 
• 18402-82-9 (3E)-oct-3-en-2-one 
• 21894-17-7 2r-chloro-3c-methyl-2-pentyl-oxirane 
• 122-56-5 tributyl borane 
• 78-94-4 methyl vinyl ketone 

Downstream Products

• 146329-67-1 (R)-3-Hydroxy-2-octanone 
• 86838-20-2 (+)-(3S)-3-hydroxyoctan-2-one 
• 111-13-7 hexyl-methyl-ketone 
• 21419-30-7 hydrochloride salt of 3-amino-2-octanone 

Relevant articles and documents

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Catalytic dehydrogenative dual functionalization of ethers: Dealkylation-oxidation-bromination accompanied by C-O bond cleavage: Via aerobic oxidation of bromide

Catalytic dehydrogenative dual functionalization (DDF) of ethers via oxidation, dealkylation, and α-bromination by the aerobic oxidation of bromide was developed to obtain the corresponding α-bromo ketones in high yields. In particular, the reaction of substituted tetrahydrofurans as cyclic ethers provided 3,3-dibromo tetrahydrofuran-2-ols in high yields selectively through the double α-bromination.

Chemoenzymatic synthesis of 'α-bichiral' synthons. Application to the preparation of chiral epoxides

Microbiological reduction of 3-bromo-2-octanone and 3-azido-2-octanone led to all the stereoisomers of 3-bromo-2-octanol and 3-azido-2-octanol. Chiral 2,3-epoxyoctanes were prepared from the 3-bromo-2-octanols.