51146-06-6

Usage

Uses

Used in Pharmaceutical Industry:
METHYL 2-HYDROXY-6-METHYLPYRIDINE-3-CARBOXYLATE is used as an intermediate in the synthesis of various pharmaceuticals, particularly those related to vitamin B6. Its role in the production process is crucial for creating medications that address specific health needs.
Used in Agrochemical Production:
METHYL 2-HYDROXY-6-METHYLPYRIDINE-3-CARBOXYLATE is also utilized in the production of agrochemicals, where it serves as a key component in the development of products designed to improve crop yields and protect plants from pests and diseases.
Used in Organic Compound Synthesis:
METHYL 2-HYDROXY-6-METHYLPYRIDINE-3-CARBOXYLATE is employed in the synthesis of other organic compounds, contributing to the creation of a wide range of chemical products used in various industries.
It is important to handle and store METHYL 2-HYDROXY-6-METHYLPYRIDINE-3-CARBOXYLATE according to proper safety guidelines due to its potential hazards if not used properly.

InChI:InChI=1/C8H9NO3/c1-5-3-4-6(7(10)9-5)8(11)12-2/h3-4H,1-2H3,(H,9,10)

Upstream product

• 186581-53-3 diazomethane 
• 38116-61-9 2-hydroxy-6-methylnicotinic acid 
• 67-56-1 methanol 
• 75-36-5 acetyl chloride 

Downstream Products

• 934361-39-4 methyl 5-chloro-2-hydroxy-6-methylpyridine-3-carboxylate 

Relevant academic research and scientific papers

PYRIDINE DERIVATIVES AS IMMUNOMODULATORS

Disclosed are pyridine derivatives of formula (I) and a pharmaceutical composition comprising the pyridine derivatives or their pharmaceutically acceptable salts or stereoisomers thereof, and at least one pharmaceutically acceptable carrier or excipient, which are useful as key intermediate for the synthesis of compounds to inhibit PD-1/PD-L1 signaling pathway or capable of inhibiting PD-1/PD-L1 signaling pathway.

SUBSTITUTED AZACYCLES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS

The present invention relates to compounds of formula (I), or their isotopic forms, stereoisomers, tautomers or pharmaceutically acceptable salt (s) thereof as muscarinic M1 receptor positive allosteric modulators (M1 PAMs). The present invention describe

An efficient synthesis of functionalized 2-pyridones by direct route or via amide/enolate ammonium salt intermediates

A number of compounds with a 2-pyridone structure 3, which have different substituents and-are analogous to cardiotonic drugs like milrinone, have been synthesized in high yields from the appropriate enamino ketones 2 using different cyanomethylene active compounds (methyl cyanoacetate, benzoylacetonitrile and phenylsulfonylacetonitrile). In this synthetic route, the active role of the dimethylamine released in situ on the cyclization process has been underlined. In particular, its direct intervention; as a nucleophile or a base, was proven and intermediate amides 5 or enolate ammonium salts 6 were isolated and recognized by the analytical and spectral data.

PYRIDINONE THROMBIN INHIBITORS

Compounds of the invention are useful in inhibiting thrombin and associated thrombotic occlusions and have the following structure: STR1 for example: STR2