51151-36-1

Upstream product

• 1271-55-2 acetylferrocene 
• 59-88-1 phenylhydrazine hydrochloride 
• 100-63-0 phenylhydrazine 

Downstream Products

• 918342-45-7 1-phenyl-3-ferrocenyl-1H-pyrazole-4-carbaldehyde 

Relevant academic research and scientific papers

Synthesis, characterization and antimicrobial activity of novel 3-ferrocenyl-2-pyrazolyl-1,3-thiazolidin-4-ones

A new series of ferrocene-containing thiazolylpyrazoles – 3-ferrocenyl-2-pyrazolyl-1,3-thiazolidin-4-ones have been synthesized using convenient one-pot three component condensation. Twelve newly synthesized compounds were fully characterized by spectroscopic (IR and NMR) and electrochemical methods (cyclic voltammetry). Single crystal X-ray structure analysis were undertaken on two compounds. The twelve novel ferrocene derivatives were also evaluated for antimicrobial activity. The results showed moderate antimicrobial activity of synthesized compounds with better effect on Candida albicans and Gram-negative bacteria than Gram-positive bacterial strains.

Antispasmodic and antimicrobial activities of pyrazole-containing ferrocenyl alkanols versus their phenyl analogs, and the entry point to potential multitarget treatment for inflammatory bowel diseases

Inflammatory bowel diseases (IBM), such as Crohn's disease, and their common complications represent a global health challenge. Many pyrazole derivatives, such as the spasmolytic drug metamizole, have already found their place among the frequently used th